874-72-6

Usage

Uses

Used in Organic Synthesis:
4-Chlorobenzylmagnesium chloride is used as an intermediate in organic synthesis for the preparation of various organic compounds. Its reactivity allows it to participate in a wide range of reactions, making it a valuable tool in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-chlorobenzylmagnesium chloride is used as a precursor for the preparation of specific pharmaceutical compounds. Its unique reactivity enables the synthesis of molecules with potential therapeutic applications.
Used in Chemical Research:
4-Chlorobenzylmagnesium chloride is also used in chemical research as a model compound to study the reactivity and properties of organomagnesium compounds. This helps researchers to better understand the underlying mechanisms of various chemical reactions and develop new synthetic strategies.
Used in the Preparation of 1-Chloro-4-(4-Methyl-3-Pentenyl)Benzene:
4-Chlorobenzylmagnesium chloride is specifically used as a precursor for the preparation of 1-chloro-4-(4-methyl-3-pentenyl)benzene by reacting with 1-bromo-3-methyl-2-butene. This reaction showcases the compound's ability to be a key intermediate in the synthesis of specific target molecules.

InChI:InChI=1/C7H6Cl.ClH.Mg/c1-6-2-4-7(8)5-3-6;;/h2-5H,1H2;1H;/q;;+1/p-1/rC7H6Cl2Mg/c8-7-3-1-6(2-4-7)5-10-9/h1-4H,5H2

Upstream product

• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 7439-95-4 magnesium 

Downstream Products

• 27980-54-7 xanthene, 9-(4-chlorophenyl)methylene 
• 77-64-5 1-(4-chloro-phenyl)-2-phenyl-4-pyrrolidino-butan-2-ol 
• 6279-35-2 2-(4'-chlorophenyl)-1-phenylethan-1-ol 
• 71512-20-4 2-(4-chlorophenyl)-N-phenylacetamide 
• 7378-50-9 (4'-chloro-trans-stilben-4-yl)-dimethyl-amine 
• 3704-94-7 1-<4-Chlor-benzyliden>-indan 
• 106897-76-1 1-chloro-4-(4-methylpent-3-en-1-yl)benzene 
• 110-86-1 pyridine 
• 366-18-7 [2,2]bipyridinyl 
• 4350-41-8 2-(4-chlorobenzyl)pyridine 
• 58661-46-4 p-benzyl-phenylsulfonylbenzene 
• 119929-98-5 p-(p-chlorobenzyl)phenylsulfonylbenzene 
• 79578-90-8 5-[1-(4-Chloro-phenyl)-meth-(Z)-ylidene]-N²,N²,N⁴,N⁴-tetraethyl-5H-imidazole-2,4-diamine 
• 95523-44-7 1-Ethyl-3-<(4-chloro-α-hydroxy)phenethyl>indole 

Relevant academic research and scientific papers

PROCESS FOR THE PREPARATION OF GRIGNARD COMPOUNDS

The invention relates to a process for the preparation of Grignard compounds using a continuous method which involves the reaction of an organic halide dissolved in an organic solvent with metallic magnesium which, together with the activator solution in an organic solvent, fills the flow reactor or optionally a system of flow reactors, and subsequently, the resulting reaction mixture is fed into the terminal flow reactor containing metallic magnesium in order to achieve complete conversion of the organic halide, whereby preferably the organic solvent is re-circulated to flow reactors in a form of vapour.

SUBSTITUTED AMINO COMPOUNDS AS 5-HT/NA UPTAKE INHIBITORS

The invention relates to substituted amino compounds, methods for the production thereof, medicaments containing said compounds, the use of said substances for producing medicaments, preferably for the treatment of depressions, anxiety attacks, pain, and renal incontinence, and methods for treating said diseases.

METHOD FOR PRODUCING 2,2-DICHLORO-12-(4-HALOPHENYL)DODECANATE SALT AND METHOD FOR PRODUCING PRODUCTION INTERMEDIATE THEREOF

Disclosed is a commercially suitable method for producing a 1-substituted-10-(4-halophenyl)decane with high yield in a short time without producing 4,4'-dichlorobiphenyl (an environmental pollutant). Also disclosed is a commercially suitable method for producing a 2,2-dichloro-12-(4-halophenyl)dodecanate salt with high yield by a simple process. Specifically disclosed is a method for producing a 1-substituted-10-(4-halophenyl)decane characterized by reacting a 4-halobenzylmagnesium halide with a 1,9-disubstituted nonane. Also specifically disclosed is a method for producing a 2,2-dichloro-12-(4-halophenyl)dodecanate salt characterized by comprising a first step for obtaining a 2,2-dichloro-12-(4-halophenyl)dodecanoic acid ester by reacting a 1-iodo-10-(4-halophenyl)decane and a dichloroacetic acid ester in the presence of a base, and a second step for converting the 2,2-dichloro-12-(4-halophenyl)dodecanoic acid ester into a 2,2-dichloro-12-(4-halophenyl)dodecanate salt. Further specifically disclosed are 1-iodo-10-(4-chlorophenyl)decane and a method for producing the same.

Fluorenyl-azolylmethyl-carbinol compounds and their medicinal use

The invention relates to fluorenylazolylmethylcarbinols and methods for their preparation. Also included are compositions containing said fluorenylazolylmethyl-carbinols and methods for the use of said carbinols and compositions containing them as antimyc