874111-16-7Relevant articles and documents
New 7,8-ethylenedioxy-2,3-benzodiazepines as noncompetitive AMPA receptor antagonists
Zappala, Maria,Pellicano, Alessia,Micale, Nicola,Menniti, Frank S.,Ferreri, Guido,De Sarro, Giovambattista,Grasso, Silvana,De Micheli, Carlo
, p. 167 - 170 (2007/10/03)
A series of 1-aryl-3,5-dihydro-7,8-ethylenedioxy-4H-2,3-benzodiazepin-4- ones 2a-f, were synthesized and screened as anticonvulsant agents in DBA/2 mice against sound-induced seizures. The new compounds display anticonvulsant properties although the EDsu