87412-75-7

Basic information

• Product Name: 1H-Pyrazolo[3,4-d]pyrimidine, 4-(2-methoxyphenyl)-1-phenyl-
• CAS NO: 87412-75-7
• Molecular Formula: C18H14N4O
• Molecular Weight: 302.335
• Mol File: 87412-75-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1H-Pyrazolo[3,4-d]pyrimidine, 4-(2-methoxyphenyl)-1-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Pyrazolo[3,4-d]pyrimidine, 4-(2-methoxyphenyl)-1-phenyl-(87412-75-7)
• EPA Substance Registry System: 1H-Pyrazolo[3,4-d]pyrimidine, 4-(2-methoxyphenyl)-1-phenyl-(87412-75-7)

Safety Data

• Hazardous Substances Data: 87412-75-7(Hazardous Substances Data)

Upstream product

• 59563-85-8 (2-methoxy-phenyl)-(1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-methanone 
• 89549-58-6 4,5-dihydro-4-(2-methoxyphenyl)-1-phenyl-1H-pyrazolo<3.4-d>pyrimidine-4-carboxylic acid 
• 5334-30-5 1-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine 
• 100-66-3 methoxybenzene 

Relevant articles and documents

Aryl Coupling Reactions of Pyrazolopyrimidin-4-yl Radicals

4-Arylpyrazolopyrimidines (4) were the subjects of a synthetic investigation in order to evaluate their biological activity.Attempts to prepare 4 from 4-aminopyrazolopyrimidines (5) via classical Gomberg-Bachmann-Hey aryl coupling conditions failed.Conversion of 5 to 4 was accomplished by diazotiazation of 5 using alkyl nitrites with an acid catalyst in aromatic solvents.Isomer distribution of the aryl-coupled products 4 was that predicted for a radical intermediate (ortho > meta ca. para); isomer structures were assigned by a detailed 1H NMR analysis.Unusual fragmentation products 17 and 18 were isolated during the course of investigations.These oxadiazoles probably arise from collapse of intermediate pyrazolopyrimidin-4-yl radicals 15.