874130-59-3Relevant articles and documents
Model studies towards the synthesis of gilvocarcin M
Cordera-Vargas, Alejandro,Quiclet-Sire, Beatrice,Zard, Samir Z.
, p. 4432 - 4443 (2005)
In model studies towards the synthesis of gilvocarcin M, a convergent, xanthate-based free-radical strategy was tested in order to construct the key aromatic ring attached to the sugar unit. The Royal Society of Chemistry 2005.
SUBSTITUTED BENZOHYDRAZIDE ANALOGS AS HISTONE DEMETHYLASE INHIBITORS
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Paragraph 00194, (2017/01/23)
Benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethyfase, including LSD1 and LSD2; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1 and/or LSD2.
Activity-Based Proteome Profiling Probes Based on Woodward's Reagent K with Distinct Target Selectivity
Qian, Yong,Schürmann, Marc,Janning, Petra,Hedberg, Christian,Waldmann, Herbert
supporting information, p. 7766 - 7771 (2016/07/07)
Woodward's reagent K (WRK) is a reactive heterocyclic compound that has been employed in protein chemistry to covalently and unspecifically label proteins at nucleophilic amino acids, notably at histidine and cysteine. We have developed a panel of WRK-der