87417-34-3

Upstream product

• 14689-79-3 (2S,5R,6R)-6-{[1-(2-Hydroxy-phenyl)-meth-(E)-ylidene]-amino}-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 
• 14689-79-3 6β-(2-hydroxy-benzylideneamino)-penicillanic acid 
• 21794-93-4 6-aminopenicillanic acid 
• 71264-14-7 N^α-(tert-butyloxycarbonyl)-L-α-aminoadipic acid α-benzhydryl ester 
• 47547-28-4 6-aminopenicillanic acid diphenylmethyl ester 
• 908093-98-1 diazodiphenylmethane 
• 87408-05-7 iso-penicillin N 
• 87422-33-1 α-benzhydryl ester of N-tert-butoxycarbonyl-(DL)-α-aminoadipic acid 
• 87408-05-7 (2S,5R,6R)-6-(5-Benzhydryloxycarbonyl-5-tert-butoxycarbonylamino-pentanoylamino)-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid benzhydryl ester 

Downstream Products

• 87417-35-4 5-[(1R,5R)-6-((R)-1-Benzhydryloxycarbonyl-2-methyl-allyl)-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-3-yl]-2-tert-butoxycarbonylamino-pentanoic acid benzhydryl ester 
• 87408-06-8 5-[(1R,5R)-6-((R)-1-Benzhydryloxycarbonyl-2-methyl-propyl)-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-3-yl]-2-tert-butoxycarbonylamino-pentanoic acid benzhydryl ester 
• 87417-35-4 (S)-5-[(1S,5S)-6-((R)-1-Benzhydryloxycarbonyl-2-methyl-allyl)-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-3-yl]-2-tert-butoxycarbonylamino-pentanoic acid benzhydryl ester 
• 87417-35-4 (S)-5-[(1R,5R)-6-((R)-1-Benzhydryloxycarbonyl-2-methyl-allyl)-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-3-yl]-2-tert-butoxycarbonylamino-pentanoic acid benzhydryl ester 
• 87408-06-8 (S)-5-[(1R,5R)-6-((R)-1-Benzhydryloxycarbonyl-2-methyl-propyl)-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-3-yl]-2-tert-butoxycarbonylamino-pentanoic acid benzhydryl ester 
• 87408-06-8 (S)-5-[(1S,5S)-6-((R)-1-Benzhydryloxycarbonyl-2-methyl-propyl)-7-oxo-4-thia-2,6-diaza-bicyclo[3.2.0]hept-2-en-3-yl]-2-tert-butoxycarbonylamino-pentanoic acid benzhydryl ester 

Relevant academic research and scientific papers

CONCERNING THE INTERMEDIACY OF MONOCYCLIC β-LACTAMS IN PENICILLIN BIOSYNTHESIS: SYNTHESIS AND ATTEMPTED BIOCONVERSION OF SECO-ISOPENICILLIN N

The title compound (3a) was synthesized as its dimer by the skeletal rearrangement of protected isopenicillin N-sulfoxide, hydrogenation, hydrolysis of the thiazoline ring, oxidative dimerization and deprotection.The reductive conversion of the dimer to m

SYNTHESIS OF 1-(1-D-CARBOXY-2-METHYLPROPYL)-3-L-(5-L-AMONOADIPAMIDO)-4-L-MERCAPTOAZETIDIN-2-ONE (SECO-ISOPENICILLIN N), A POTENTIAL INTERMEDIATE IN PENICILLIN BIOSYNTHESIS.

The title compound has efficiently been synthesized by the skeletal rearrangement of the protected isopenicillin N sulfoxide and the subsequent hydrolysis of the thiazoline ring.