87418-78-8

Basic information

• Product Name: 1-{(2R,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-4-hydroxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione
• CAS NO: 87418-78-8
• Molecular Weight: 630.813
• Mol File: 87418-78-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-{(2R,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-4-hydroxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-{(2R,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-4-hydroxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione(87418-78-8)
• EPA Substance Registry System: 1-{(2R,3S,4R,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-4-hydroxy-5-[(4-methoxy-phenyl)-diphenyl-methoxymethyl]-tetrahydro-furan-2-yl}-1H-pyrimidine-2,4-dione(87418-78-8)

Safety Data

• Hazardous Substances Data: 87418-78-8(Hazardous Substances Data)

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 87418-73-3 5'-O-monomethoxytritylarabinouridine 
• 3736-77-4 2,2'-Anhydrouridine 
• 3083-77-0 araU 
• 351523-07-4 3',5'-di-O-(tetrahydropyran-2-yl)-2,2'-O-cyclouridine 
• 157024-75-4 9-<3,5-di-O-(tetrahydropyran-2-yl)-β-D-arabinofuranosyl>uracil 
• 14470-28-1 mono-4-methoxytrityl chloride 

Downstream Products

• 122591-37-1 5'-O-monomethoxytritylarabinouridine-3'-O-acetyl-2'-O-N,N-diisopropyl-β-cyanoethylphosphoramidite 
• 122591-38-2 5'-O-MMT-3'-O-acetylarabinouridine 

Relevant articles and documents

The preparation of protected arabinonucleosides

A general procedure is described for the preparation of protected arabinonucleosides.Protection at the 5'-position involves triphenylmethyl groups (DMT and MMT) while the tert-butyldimethylsilyl (TBDMS) group is used to protect the 2'- or 3'-positions.The