874196-06-2Relevant academic research and scientific papers
Efficient synthesis of 6-amino-substituted pyridin-2(1H)-ones using in situ generated propiolic acid chloride
Schirok, Hartmut,Alonso-Alija, Cristina,Michels, Martin
, p. 3085 - 3094 (2007/10/03)
A regioselective and highly efficient synthesis of 6-amino-substituted pyridin-2(1H)-ones is presented. In situ generated propiolic acid chloride was used for the cyclization of acyclic β-keto N,S-acetals to afford the heterocyclic core. Substitution by a
