874196-41-5

Upstream product

• 41478-45-9 Diethyl<(2-benzyloxy)ethyl>malonate 
• 107-15-3 ethylenediamine 

Downstream Products

• 874196-43-7 N,N'-bis(2-tert-butoxycarbonylamino-ethyl)-2-(2-benzyloxyethyl)-1,3-di(tert-butoxycarbonylamino)propane 
• 874196-42-6 N,N'-bis(2-amino-ethyl)-2-(2-benzyloxyethyl)-1,3-diaminopropane 

Relevant academic research and scientific papers

APOPTOSIS IMAGING AGENTS BASED ON LANTIBIOTIC PEPTIDES

The present invention relates to radiopharmaceutical imaging in vivo of apoptosis. The invention provides imaging agents which target apoptotic cells via selective binding to the aminophospholipid phosphatidylethanolamine (PE), which is exposed on the surface of apoptotic cells. The radiopharmaceuticals comprise radiometal complexes of chelator conjugates of PE-binding peptides. Also provided are pharmaceutical compositions, kits and methods of in vivo imaging.