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3-iodo-2-methoxy-benzaldehyde is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

874347-49-6

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874347-49-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 874347-49-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,3,4 and 7 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 874347-49:
(8*8)+(7*7)+(6*4)+(5*3)+(4*4)+(3*7)+(2*4)+(1*9)=206
206 % 10 = 6
So 874347-49-6 is a valid CAS Registry Number.

874347-49-6Relevant academic research and scientific papers

Monodentate Transient Directing Group-Assisted Palladium-Catalyzed Direct ortho-C-H Iodination of Benzaldehydes for Total Synthesis of Hernandial

Chen, Xuerong,La, Ming,Liu, Dandan,Zhang, Fang-Lin,Zhou, Yirong

supporting information, p. 9184 - 9188 (2021/11/30)

The first palladium-catalyzed direct o-C-H iodination of benzaldehydes was successfully developed with the assistance of commercially available 2,5-bis(trifluoromethyl)aniline as the optimal monodentate transient directing group (MonoTDG). Moderate to exc

BETA-LACTAMASE INHIBITORS

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Paragraph 00323, (2014/06/24)

Described herein are compounds and compositions that modulate the activity of beta-lactamases. In some embodiments, the compounds described herein inhibit beta-lactamase. In certain embodiments, the compounds described herein are useful in the treatment of bacterial infections.

Compounds and Methods for Inhibiting the Interaction of BCL Proteins with Binding Partners

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Page/Page column 109-110, (2008/12/05)

The invention relates to isoxazolidine containing compounds that bind to bcl proteins and inhibit Bcl function. The compounds may be used for treating and modulating disorders associated with hyperproliferation, such as cancer.

Compounds and methods for inhibiting the interaction of BCL proteins with binding partners

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Page/Page column 20-21, (2010/11/27)

The present invention relates to heterocyclic compounds that bind to Bcl proteins and inhibit Bcl function, compositions comprising such compounds, and methods for treating and modulating disorders associated with hyperproliferation, such as cancer.

Iodination of Methylated Anisoles: Unusual Aryl Methyl Replacement and Oxidations

Panetta, Charles A.,Fang, Zheng,Mattern, Daniell L.

, p. 7953 - 7958 (2007/10/03)

The treatment of methylated anisoles with iodine, periodic acid, sulfuric acid, and aqueous acetic acid has resulted in iododemethylations and/or aryl methyl oxidations in addition to the expected mono- and diiodinations of the aromatic ring.Four dimethylanisoles and o-methylanisole were treated under identical conditions.Iododemethylations were observed in three of the four dimethylanisoles and aryl methyl oxidations to benzaldehydes occured with o-methylanisole and two of the dimethylanisoles.No precedence could be found for either of these reactions under the experimental conditions employed.Several possible mechanisms are discussed for these transformations.Some experimental evidence suggests that methyl oxidation to a benzaldehyde could be a prerequisite for an iododemethylation via an iodonium ion-assisted reverse Gatterman-Koch reaction; single-electron-transfer or classical electrophilic mechanisms are also consistent with the iododemethylations.

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