23602-64-4Relevant academic research and scientific papers
Microwave synthesis and crystal structure of 2-hydroxy-3-iodobenzaldehyde- copper (II)
Xu, Suo-Ping,Wang, Xiao-Liang,Tang, Jian-Feng,Ruan, Ban-Feng,Zhu, Hai-Liang
, p. 82 - 84 (2011)
One new complex, 2-hydroxy-3-iodo-benzaldehyde-copper (II) has been designed and microwave synthesized. The structure was determined by UV, IR and single X-ray crystallography study. The title complex C14H 8CuI2O4 crystallizes in the orthorhombic space group Pna21 with the cell parameters a = 12.7897(12) A, b = 6.1132(8) A, c = 19.5114(18) A, V = 1525.5(3) A3 and Z = 4. The central copper (II) is four-coordinated by four oxygen atoms from two 3-iodosalicylaldehyde. The complex is linked into rhombic crystals by weak intermolecular interactions. Springer Science+Business Media, LLC 2010.
Synthesis of a 4,6-disubstituted dibenzofuran β-sheet initiator by reductive radical arylation of benzene
Crich, David,Grant, Daniel
, p. 2384 - 2386 (2005)
(Chemical Equation Presented) Tributyltin hydride mediated addition of 3-iodosalicylaldehyde to benzene in the presence of catalytic benzeneselenol affords (1,4-cyclohexadien-3-yl)salicylaldehyde. Homologation of the aldehyde group is followed by cycloeth
Diversely halogenated spiropyrans - Useful synthetic building blocks for a versatile class of molecular switches
Schulz-Senft, Mathias,Gates, Paul J.,S?nnichsen, Frank D.,Staubitz, Anne
, p. 292 - 301 (2016/09/09)
Spiropyrans are dyes that can be reversibly switched to a highly colored merocyanine form by a number of stimuli such as light, mechanical force or temperature. To make use of these molecules, there is a requirement to functionalize them appropriately. Herein we report a library of spiropyrans bearing two (pseudo) halide functional groups on either half of the molecule. Such halide substituents are valuable, because they themselves may be used as reactive sites in cross-coupling reactions, for example. Different combinations of halides, for which different reactivities in cross-coupling reactions may be expected, will facilitate selective consecutive cross-coupling reactions and condensations. Data concerning the UV/vis characteristics, the photostationary equilibria of the materials as well as the half-life of the merocyanine forms in solution are presented.
OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE
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Page/Page column 31, (2014/12/09)
A process for the otigomerisation of ethylene to predominantly 1-hexene or 1-octene or mixtures of 1-hexene and 1-octene includes contacting ethylene with a catalyst under ethylene oligomerisation conditions. The catalyst comprises a source of chromium, a diphosphine ligating compound, and optionally an activator. The diphosphine ligating compound includes at least one optionally substituted fused cyclic structure including at least two rings, the optionally substituted fused cyclic structure including a 5- to 7- membered aromatic first ring bonded to a phosphorus atom, the aromatic first ring being fused to a 4- to 8-membered heterocyclic second ring, the heterocyclic second ring including a heteroatom which is separated by two ring atoms along the shortest connecting path from the phosphorous atom that is bonded to the first aromatic ring.
OLIGOMERISATION OF ETHYLENE TO MIXTURES OF 1-HEXENE AND 1-OCTENE
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Page/Page column 30, (2014/12/09)
A process for the oligomerisation, preferably the tetramerisation, of ethylene to predominantly 1- hexene or 1-octene or mixtures of 1-hexene and 1-octene includes contacting ethylene with a catalyst under ethylene oiigomerisation conditions. The catalyst
Synthesis of conformationally constrained benzoylureas as BH3-mimetics
Brady, Ryan M.,Hatzis, Effie,Connor, Theresa,Street, Ian P.,Baell, Jonathan B.,Lessene, Guillaume
supporting information; experimental part, p. 5230 - 5237 (2012/08/08)
The design of small molecules that mimic the BH3 domain and bind to Bcl-2 proteins has emerged as a promising approach to discovering novel anti-cancer therapeutics. We reveal the design and synthesis of conformationally constrained benzoylurea scaffolds as conformational probes. Central to helix mimicry, the intramolecular hydrogen bond in the benzoylurea plays a key role in the pre-organisation of the acyclic substrates for cyclisation via ring closing metathesis, providing efficient access to the constrained mimetics. The Royal Society of Chemistry 2012.
Synthesis of halogenated phenols by directed ortho-lithiation and ipso-iododesilylation reactions of O-aryl N-isopropylcarbamates
Kauch, Matthias,Hoppe, Dieter
, p. 1578 - 1589 (2007/10/03)
The regioselective synthesis of halogenated phenols via directed ortho-lithiation reactions of in situ N-silylated O-aryl N-isopropylcarbamates is reported. This protocol is complemented by ipso-iododesilylation reactions of C-silylated carbamates and iodine-magnesium exchange reactions, which are facilitated by the adjacent carbamoyl group. These methods provide an entry into a series of o-fluoro-, o-iodo-, and o,o′-diiodophenols in high yields which are otherwise difficult to obtain. Georg Thieme Verlag Stuttgart.
One-pot synthesis of ortho-hydroxycinnamate esters
Anwar, Hany F.,Skatteb?l, Lars,Skramstad, Jan,Hansen, Trond Vidar
, p. 5285 - 5287 (2007/10/03)
Phenols are converted to salicylaldehydes with paraformaldehyde, MgCl 2-Et3N in THF, and subsequent treatment with methyl (triphenylphosphoranylidene)acetate gave the corresponding methyl ortho-hydroxycinnamate derivatives. The sequence is conveniently carried out as a one-pot procedure.
Diazonamide synthesis studies: Use of negishi coupling to fashion diazonamide-related biaryls with defined axial chirality
Feldman, Ken S.,Eastman, Kyle J.,Lessene, Guillaume
, p. 3525 - 3528 (2007/10/03)
(matrix presented) The syntheses of a bis indole and an indole salicylate with the required axial chirality for diazonamide A are reported. Atropselectivity in these biaryl systems is enforced by an sp3 stereogenic center in a lactone tether in
