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87450-10-0

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87450-10-0 Usage

Description

Propargyl-PEG5-alcohol enables Click Chemistry reactions with azide compounds or biomolecules via copper catalyzed azide-alkyne Click Chemistry to yield a stable triazole linkage.

Check Digit Verification of cas no

The CAS Registry Mumber 87450-10-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,4,5 and 0 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 87450-10:
(7*8)+(6*7)+(5*4)+(4*5)+(3*0)+(2*1)+(1*0)=140
140 % 10 = 0
So 87450-10-0 is a valid CAS Registry Number.

87450-10-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[2-[2-(2-prop-2-ynoxyethoxy)ethoxy]ethoxy]ethanol

1.2 Other means of identification

Product number -
Other names 15-hydroxy-4,7,10,13-tetraoxapentadec-1-yne

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:87450-10-0 SDS

87450-10-0Relevant articles and documents

Synthesis of Two-Photon Active Tricomponent Fluorescent Probe for Distinguishment of Biotin Receptor Positive and Negative Cells and Imaging 3D-Spheroid

Pal, Kaushik,Sharma, Aman,Koner, Apurba L.

, p. 6425 - 6429 (2018)

A fluorescence microscopy-based distinguishment between biotin receptor (BiR) positive and negative cell lines via receptor-mediated endocytosis has been demonstrated. A water-soluble, three-component, two-photon (2P) active solvatofluorochromic probe has been designed and synthesized. The applicability of the probe for 2P microscopy and 3D-spheroid was also assessed.

Development of PDT/PET Theranostics: Synthesis and Biological Evaluation of an 18F-Radiolabeled Water-Soluble Porphyrin

Entract, Guy M.,Bryden, Francesca,Domarkas, Juozas,Savoie, Huguette,Allott, Louis,Archibald, Stephen J.,Cawthorne, Chris,Boyle, Ross W.

, p. 4414 - 4423 (2015)

Synthesis of the first water-soluble porphyrin radiolabeled with fluorine-18 is described: a new molecular theranostic agent which integrates the therapeutic selectivity of photodynamic therapy (PDT) with the imaging efficacy of positron emission tomograp

A bioorthogonal turn-on fluorescent strategy for the detection of lysine acetyltransferase activity

He, Maomao,Han, Zhen,Qiao, Jing,Ngo, Liza,Xiong, May P.,Zheng, Y. George

, p. 5594 - 5597 (2018)

Lysine acetylation plays vital roles in the regulation of fundamental cellular processes, which is mediated by lysine acetyltransferases (KATs). Developing chemical biology probes for KAT activity detection is of important value in providing improved understanding of their biological functions. We reported a panel of "turn-on" fluorescent probes for sensitive and selective detection of KAT enzymatic activity through a simple mix-and-read format. Combined with bioorthogonal substrate labelling and click chemistry, these probes produced strong "turn-on" fluorescent signals in response to KAT-mediated acylation process. This chemical biology strategy diversifies the assay toolboxes to investigate functions and mechanisms of acetyltransferase enzymes.

Functionalized 2-Hydroxybenzaldehyde-PEG Modules as Portable Tags for the Engagement of Protein Lysine ?-Amino Groups

Sacco, Giovanni,Stammwitz, Simon,Belvisi, Laura,Pignataro, Luca,Dal Corso, Alberto,Gennari, Cesare

supporting information, p. 1763 - 1767 (2021/03/24)

The formation of reversible-covalent interactions between a small-molecule ligand and its protein target is emerging as a general strategy to design binders with increased affinity. In this context, 2-hydroxybenzaldehyde (2HB) has been recently proposed a

DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INIDBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE

-

Paragraph 0151; 0152, (2021/02/05)

Disclosed herein are novel bifunctional compounds formed by conjugating BTK inhibitor moieties with E3 ligase Ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation, and methods of preparation and uses thereof.

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