87451-54-5

Upstream product

• 87507-55-9 methyl 5-oxo-endo-bicyclo<2.2.2>octane-2-carboxylate 
• 87451-52-3 methyl 5-ethylenedioxy-endo-bicyclo<2.2.2>octane-2-carboxylate 
• 87451-53-4 2-(ethylenedioxy)-5-endo-(hydroxymethyl)bicyclo<2.2.2>octane 
• 98-59-9 p-toluenesulfonyl chloride 

Relevant academic research and scientific papers

Stereochemistry of Horse Liver Alcohol Dehydrogenase Mediated Oxidoreduction of 2-Brendanone Type Cage-Shaped Tricyclic Ketones and the Related Stereoisomeric Alcohols

For elucidation of the origin of the inertness exhibited by 2-twist-brendanone type ketones 1 toward microbial and HLADH-catalyzed reductions, the stereochemistry of the oxidoreduction of 2-brendanone type ketones 5 and the related alcohols 14 was studied by preparative-scale incubation experiments.Oxidoreduction of 2-brendanone type substrates 5 and 14 by the HLADH-NAD(+) system was found to proceed with much higher rates than those of the 2-twist-brendanone type substrates 1 and 10.The steric courses found in these enzymatic processes were compared with those of microbial processes.