874660-57-8

Basic information

• Product Name: ((3aS,4R,6R,7aS)-6-Allyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethoxy)-tert-butyl-diphenyl-silane
• Synonyms: ((3aS,4R,6R,7aS)-6-Allyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethoxy)-tert-butyl-diphenyl-silane
• CAS NO: 874660-57-8
• Molecular Weight: 466.693
• Mol File: 874660-57-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: ((3aS,4R,6R,7aS)-6-Allyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethoxy)-tert-butyl-diphenyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: ((3aS,4R,6R,7aS)-6-Allyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethoxy)-tert-butyl-diphenyl-silane(874660-57-8)
• EPA Substance Registry System: ((3aS,4R,6R,7aS)-6-Allyl-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethoxy)-tert-butyl-diphenyl-silane(874660-57-8)

Safety Data

• Hazardous Substances Data: 874660-57-8(Hazardous Substances Data)

Upstream product

• 91376-49-7 (S)-1-(tert-butyldiphenylsilyloxy)-2-hydroxy-3-butene 
• 58479-61-1 tert-butylchlorodiphenylsilane 
• 106731-74-2 tert-butyl[(2S)-oxiran-2-ylmethoxy]diphenylsilane 
• 874660-33-0 (3aS,4R,6R,7aS)-6-Allyl-4-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2-one 
• 874660-55-6 4-(tert-butyl-diphenyl-silanyloxymethyl)-6-ethoxy-tetrahydro-[1,3]dioxolo[4,5-c]pyran-2-one 
• 874660-31-8 (2R,3S,4S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-ethoxy-tetrahydro-pyran-3,4-diol 
• 874660-28-3 tert-butyl-[2-(1-ethoxy-but-3-enyloxy)-but-3-enyloxy]-diphenyl-silane 
• 874660-54-5 tert-butyl-(6-ethoxy-5,6-dihydro-2H-pyran-2-ylmethoxy)-diphenyl-silane 
• 874660-56-7 (2R,3S,4S,6R)-6-Allyl-2-(tert-butyl-diphenyl-silanyloxymethyl)-tetrahydro-pyran-3,4-diol 
• 77-76-9 2,2-dimethoxy-propane 

Downstream Products

• 874660-13-6 (3aS,4S,6R,7aS)-6-(3-Benzyloxy-propyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-carbaldehyde 
• 874660-59-0 [(3aS,4R,6R,7aS)-6-(3-Benzyloxy-propyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-yl]-methanol 
• 874660-58-9 [(3aS,4R,6R,7aS)-6-(3-Benzyloxy-propyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-4-ylmethoxy]-tert-butyl-diphenyl-silane 
• 874660-34-1 3-[(3aS,4R,6R,7aS)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-2,2-dimethyl-tetrahydro-[1,3]dioxolo[4,5-c]pyran-6-yl]-propan-1-ol 

Relevant articles and documents

Enantioselective total synthesis of brevetoxin A: Unified strategy for the B, E, G, and J subunits

Brevetoxin A is a decacyclic ladder toxin that possesses 5-, 6-, 7-, 8-, and 9-membered oxacycles, as well as 22 tetrahedral stereocenters. Herein, we describe a unified approach to the B, E, G, and J rings based upon a ring-closing metathesis strategy from the corresponding dienes. The enolate technologies developed in our laboratory allowed access to the precursor acyclic dienes for the B, E, and G medium-ring ethers. The strategies developed for the syntheses of these four monocycles ultimately provided multigram quantities of each of the rings, supporting our efforts toward the completion of a convergent synthesis of brevetoxin A.