874758-84-6 Usage
Uses
Used in Pharmaceutical Industry:
2-Chloro-4-pyrrolidin-1-yl-pyridine is utilized as a key intermediate in the synthesis of drugs and active pharmaceutical ingredients. Its distinctive chemical structure contributes to the development of novel drug candidates, enhancing the therapeutic potential for various medical conditions.
Used in Medicinal Chemistry Research:
2-CHLORO-4-PYRROLIDIN-1-YL-PYRIDINE is employed as a subject of research in medicinal chemistry, where its antitumor and antiviral properties are being investigated. The exploration of these properties is crucial for identifying new therapeutic agents that could address unmet medical needs and contribute to the advancement of healthcare.
Used in Drug Development:
2-Chloro-4-pyrrolidin-1-yl-pyridine is used as a building block in drug development, where its incorporation into new molecular entities can lead to the creation of innovative pharmaceuticals with improved efficacy and safety profiles. Its versatility in chemical synthesis makes it an important component in the design of next-generation therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 874758-84-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,7,5 and 8 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 874758-84:
(8*8)+(7*7)+(6*4)+(5*7)+(4*5)+(3*8)+(2*8)+(1*4)=236
236 % 10 = 6
So 874758-84-6 is a valid CAS Registry Number.
874758-84-6Relevant articles and documents
Preparative-Scale Synthesis of Vedejs Chiral DMAP Catalysts
Kinens, Artis,Balkaitis, Simonas,Suna, Edgars
, p. 12449 - 12459 (2018/10/20)
A scalable synthesis of chiral Vedejs-type DMAP catalysts is reported. The key step of the synthesis is amination of the enantiomerically pure 4-chloropyridine derivative using well-defined ZnCl2(amine)2 complexes. A series of Zn(II)-amine complexes have been synthesized to explore the scope of the ZnCl2-mediated amination of 4-halopyridines. Mechanistic studies support a Zn(II)-facilitated nucleophilic aromatic substitution as a plausible mechanism for the chlorine-to-amine exchange.
Pyrrolidine-containing polypyridines: New ligands for improved visible light absorption by ruthenium complexes
Martineau, David,Beley, Marc,Gros, Philippe C.
, p. 566 - 571 (2007/10/03)
A range of new electron-releasing pyrrolidine-containing bipyridines and terpyridines has been prepared via selective metalation-cross-coupling sequences. The obtained ligands have been involved in microwave-assisted ruthenium complexation leading to homoleptic complexes in high yield. The electron-donor effect of the pyrrolidine nucleus led to a notable improvement of visible light absorption and strong changes in the electrochemical behavior, opening new opportunities for the design of photovoltaic devices.
