87476-76-4Relevant academic research and scientific papers
BENZO-FUSED HETEROCYCLIC ANTI-ULCER AGENTS
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, (2008/06/13)
Compounds of the formula: STR1 wherein B is a moiety having the formula: STR2 R is mono-or dihalo, amino, nitro, cyano, hydroxy, trifluoromethyl, mercapto, lower alkyl, lower alkoxy, alkanoyl, cycloalkyl of 4-7 carbon atoms, carboxy, alkoxycarbonyl, mono-or di-lower alkyl substituted amino, alkanoylamino, lower alkyl thio, lower alkylsulfonyl, sulfamoyl, lower alkyl substituted sulfamoyl, phenyl or phenyl substituted with halo, lower alkyl, lower alkoxy, trifluoromethyl, hydroxy, amino, cyano or nitro.X is SO 2, SO, S or C=O; andA is amine selected from the group STR3 , wherein R 1 is hydrogen or R 2 CH 2 wherein R 2 is mono-or diloweralkylamino, mono-or di-N-lower alkylaminoloweralkyl, (2-furyl) methylamino, benzylamino, lowercycloalkylamino, 1-pyrrolidinyl, 1-piperidinyl, 1-hexahydroazepinyl, 1-octahydroazocinyl, 3-thiazolidinyl, 4-morpholinyl or 4-thiomorpholinyl; R 3 is hydrogen or (1-piperidinyl) methyl with the proviso that when R 3 is (1-piperidinyl)methyl, R 1 is hydrogen; n is 1 to 4, and the pharmacologically acceptable salts thereof.
