874771-70-7Relevant articles and documents
Total synthesis of racemosol and de-O-methylracemosol, potent cyclooxygenase (COX) inhibitors and antimalarial agents
Sae-Lao, Patcharaporn,Kittakoop, Prasat,Rajviroongit, Shuleewan
, p. 345 - 348 (2007/10/03)
The total synthesis of antimalarial and cyclooxygenase inhibitors, racemosol and de-O-methylracemosol, is described. The key steps involved the lateral lithiation reaction of ortho-methyl tolulate and the pyran formation via a tandem demethylation-cycliza