874774-61-5 Usage
Uses
Used in Pharmaceutical Industry:
1-(2,6-Difluorobenzyl)piperazine is used as a potential therapeutic agent for various medical conditions due to its demonstrated biological activities. It is being investigated for its potential as an anticancer agent, targeting cancer cells and exhibiting inhibitory effects on tumor growth and progression.
Additionally, 1-(2,6-Difluorobenzyl)piperazine is being studied for its possible use in the treatment of neurological disorders, given its potential to modulate specific signaling pathways and neurotransmitter systems involved in these conditions.
Furthermore, 1-(2,6-DIFLUOROBENZYL)PIPERAZINE has shown promise as a candidate for the development of antidepressant and anxiolytic medications, offering potential relief for patients suffering from mood and anxiety disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 874774-61-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,7,4,7,7 and 4 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 874774-61:
(8*8)+(7*7)+(6*4)+(5*7)+(4*7)+(3*4)+(2*6)+(1*1)=225
225 % 10 = 5
So 874774-61-5 is a valid CAS Registry Number.
874774-61-5Relevant academic research and scientific papers
Design and Synthesis of Novel Insecticides Based on the Serotonergic Ligand 1-[(4-Aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine(PAPP)
Cai, Mingyi,Li, Zhong,Fan, Feng,Huang, Qingchun,Shao, Xusheng,Song, Gonghua
experimental part, p. 2624 - 2629 (2011/07/31)
1-[(4-Aminophenyl)ethyl]-4-[3-(trifluoromethyl)phenyl]piperazine (PAPP) is a 5-HT1A agonist and was reported to display high affinity for serotonin (5-HT) receptor from the parasitic nematode Haemonchus contortus. The present investigation explored the possibility of using PAPP as a lead compound of new insecticides with novel mode of action. On the basis of the PAPP scaffold, a series of 1-arylmethyl-4-[(trifluoromethyl)pyridin-2-yl]piperazine derivatives were designed, synthesized, and evaluated for biological activities against the armyworm Pseudaletia separata (Walker). Bioassays showed that most of the target compounds displayed certain growth-inhibiting activities or larvicidal activities against armyworm. The quantitative structure-activity relationship (QSAR) for growth-inhibiting activities was also analyzed and established.
