874841-30-2Relevant academic research and scientific papers
Improved Substrate Scope in the Potassium Hexacyanoferrate(II)-Based Cyanation for the Synthesis of Benzonitriles and Their Heterocyclic Analogues
Richardson, Jeffery,Mutton, Simon P.
, p. 4922 - 4931 (2018/05/22)
The use of Pd(DPEPhos)Cl2 (P26) as a catalyst for the formation of benzonitriles and their heterocyclic analogues provides excellent complementarity to existing catalysts, allowing highly electron-deficient heterocyclic aryl halides to be effic
Discovery and characterization of potent and selective 4-oxo-4-(5-(5- phenyl-1,2,4-oxadiazol-3-yl)indolin-1-yl)butanoic acids as S1P1 agonists
Buzard, Daniel,Han, Sangdon,Thoresen, Lars,Moody, Jeanne,Lopez, Luis,Kawasaki, Andrew,Schrader, Thomas,Sage, Carleton,Gao, Yinghong,Edwards, Jeff,Barden, Jeremy,Thatte, Jayant,Fu, Lixia,Solomon, Michelle,Liu, Ling,Al-Shamma, Hussien,Gatlin, Joel,Le, Minh,Xing, Charles,Espinola, Sheryll,Jones, Robert M.
scheme or table, p. 6013 - 6018 (2011/10/19)
S1P1 receptor driven lymphopenia has proven utility in the treatment of an array of autoimmune disease states. As a part of our efforts to develop potent and selective S1P1 receptor agonists, we have identified a novel chemical series of 4-oxo-4-(5-(5-phenyl-1,2,4-oxadiazol-3-yl) indolin-1-yl)butanoic acid S1P1 receptor agonists.
