874921-57-0Relevant articles and documents
Tandem Horner-Wadsworth-Emmons olefination/Claisen rearrangement/hydrolysis sequence: Remarkable acceleration in water with microwave irradiation
Quesada, Ernesto,Taylor, Richard J. K.
, p. 3193 - 3195 (2005)
A tandem three-step, one-pot method for the conversion of aldehydes into β-substituted-2-oxohex-5-enoic acids 1 in good to excellent yield is described. The optimised sequence is carried out in water with microwave irradiation and involves sequential Horn