87508-50-7

Upstream product

• 62-53-3 aniline 
• 60456-23-7 (S)-oxiranemethanol 

Downstream Products

• 87508-42-7 (R)-5-(hydroxymethyl)-3-phenyl-2-oxooxazolidine 
• 99827-73-3 (S)-5-(hydroxymethyl)-3-phenyloxazolidin-2-one 
• 104392-60-1 (R)-<5-(hydroxymethyl)-3-phenyl-2-oxooxazolidinyl>-methyl 4-methylbenzenesulfonate 
• 104392-66-7 (R)-2-<(3-phenyl-2-oxo-5-oxazolidinyl)methyl>phthalimide 
• 87508-45-0 (R)-4-[5-(hydroxymethyl)-2-oxo-3-oxazolidinyl]benzenesulfonamide 
• 96800-34-9 (R)-(3-phenyl-2-oxo-5-oxazolidinyl)methyl azide 
• 121373-19-1 (R)-5-(fluoromethyl)-3-phenyl-2-oxooxazolidine 
• 96800-11-2 (S)-N-<<3-<4-(chlorosulfonyl)phenyl>2-oxo-5-oxazolidinyl>methyl> acetamide 
• 96800-17-8 (S)-N-<<3-phenyl-2-oxo-5-oxazolidinyl>methyl>acetamide 

Relevant academic research and scientific papers

Magnesium chloride (MgCl2) catalyzed highly regioselective C-3 ring opening of 2,3 epoxy alcohols by N-nucleophile

We herein report Magnesium chloride (MgCl2) catalyzed first highly C3-selective ring-opening reaction of various 2,3-epoxy alcohols with assorted N-Nucleophiles and sodium azide to furnish 3-amino-1,2 diols and 3-azido-1,2 diols respectively in high yields under mild reaction conditions. This protocol attributes the use of catalytic amount of Magnesium chloride (MgCl2), simple reaction conditions, practical operation and broad functional group tolerance.