96800-34-9Relevant articles and documents
Polymer-aided stereodivergent synthesis (PASS): A new concept for the discrete preparation of optical antipodes
Ten Holte, Peter,Thijs, Lambertus,Zwanenburg, Binne
, p. 1093 - 1095 (2007/10/03)
A new concept to the discrete prepartion of optical antipodes is reported. The approach makes use of a cyclization/cleavage procedure that has been applied to polymer-supported quasi-meso compound 1, containing a polymeric leaving group and a regular leaving group. Two-directional cyclization leads to the formation and separation of quasi-enantiomers 2 and 3 simultaneously, with one being immobilized and on free in solution. Treatment of 2 and 3 with appropriate nucleophiles gives discrete enantiomers 4 and 5.
A short synthesis of oxazolidinone derivatives linezolid and eperezolid: A new class of antibacterials
Lohray, Braj B.,Baskaran, Sundarababu,Rao, B. Srinivasa,Reddy, B. Yadi,Rao, I. Nageswara
, p. 4855 - 4856 (2007/10/03)
Oxazolidinone derivatives such as Linezolid and Eperazolid, which are a new class of antibacterials, have been synthesized from 1,2,5,6-dianhydro- 3,4-isopropylidine-D-mannitol in good yield.