87510-14-3Relevant academic research and scientific papers
COMPOUNDS CONTAINING AN ALICYCLIE STRUCTURE AND ANTI-TUMOR APPLICATION
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Paragraph 0071, (2014/03/21)
This invention relates with anti-tumor activities of new compounds containing an adamantyl group or analogs thereof. The invention also relates with the medication applications of anti-tumor and other diseases by this kind of compounds with the combination of S, P, T structures containing adamantyl group and the formation of stereoisomer, tautomers, prodrug, pharmaceutically acceptable salts, complex salts or solvates to their anticancer application and anticancer agents, which have the following general formula:
1-Azaadamantanes from Substituted Phloroglucinols
Risch, Nikolaus
, p. 4849 - 4856 (2007/10/02)
The heterocycles 3 are synthesised from substituted phloroglucinols 2 and hexamethylenetetramine in one step.Special chemical properties of these 1-azaadamantanes are, for example, the formation of a BH3-complex 4 and the stereoselective reduction to the trialcohol 6.The reaction of 6 with trimethoxymethane yields the heterodiamantane.
