875210-74-5

Upstream product

• 1885-14-9 phenyl chloroformate 
• 22483-09-6 2,2-dimethoxyethylamine 

Downstream Products

• 944580-11-4 (R)-N-(3,5-dichlorophenyl)-2-[3-(2,2-dimethoxyethyl)ureido]-2-methyl-3-(4-trifluoromethoxyphenyl)propionamide 
• 875210-73-4 (R)-2-[(4',4'-dimethoxyethyl)aminocarbonyl]amino-2-(4-bromobenzyl)-N-(3,5-dichlorophenyl)-propionamide 
• 875210-70-1 (R)-2-[(4',4'-dimethoxyethyl)aminocarbonyl]amino-2-(4-pyrimidin-5-yl-benzyl)-N-(3,5-dichlorophenyl)-propionamide 
• 1159735-65-5 (R)-3-(4-cyano-phenyl)-N-(3,5-dichloro-4-fluoro-phenyl)-2-[3-(2,2-dimethoxy-ethyl)-ureido]-2-methyl-propionamide 

Relevant academic research and scientific papers

Efficient synthesis of a small molecule, nonpeptide inhibitor of LFA-1

Figure Presented. A three-stage process for the synthesis of LFA-1 inhibitor 1 from amine 4 with an overall yield of 65% is described. The key stage involves a Ph3PCl2-induced dehydration/cyclization of urea 6 followed by a regiosele

Nitrogen heterocycles

The invention relates to nitrogen heterocycles which are histamine H-2 antagonists and which inhibit gastric acid secretion. According to the invention there is provided a guanidine derivative of the formula I:- STR1 in which R1 and R2/su