875210-74-5Relevant academic research and scientific papers
Efficient synthesis of a small molecule, nonpeptide inhibitor of LFA-1
Wang, Xiao-Jun,Xu, Yibo,Zhang, Li,Krishnamurthy, Dhileepkumar,Wirth, Thomas,Nicola, Thomas,Senanayake, Chris H.
, p. 4412 - 4415 (2010)
Figure Presented. A three-stage process for the synthesis of LFA-1 inhibitor 1 from amine 4 with an overall yield of 65% is described. The key stage involves a Ph3PCl2-induced dehydration/cyclization of urea 6 followed by a regiosele
Nitrogen heterocycles
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, (2008/06/13)
The invention relates to nitrogen heterocycles which are histamine H-2 antagonists and which inhibit gastric acid secretion. According to the invention there is provided a guanidine derivative of the formula I:- STR1 in which R1 and R2/su
