87522-28-9

Basic information

• Product Name: cis-2-benzyl-4-hydroxy-3-phenyl-3,4-dihydro-1(2H)-isoquinolone
• CAS NO: 87522-28-9
• Molecular Weight: 329.398
• Mol File: 87522-28-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: cis-2-benzyl-4-hydroxy-3-phenyl-3,4-dihydro-1(2H)-isoquinolone(CAS DataBase Reference)
• NIST Chemistry Reference: cis-2-benzyl-4-hydroxy-3-phenyl-3,4-dihydro-1(2H)-isoquinolone(87522-28-9)
• EPA Substance Registry System: cis-2-benzyl-4-hydroxy-3-phenyl-3,4-dihydro-1(2H)-isoquinolone(87522-28-9)

Safety Data

• Hazardous Substances Data: 87522-28-9(Hazardous Substances Data)

Upstream product

• 87-41-2 2-benzofuran-1(3H)-one 
• 780-25-6 N-benzylidene benzylamine 

Downstream Products

• 87522-38-1 2-benzyl-4-phenylisoquinolin-1(2H)-one 
• 87522-42-7 Acetic acid (3R,4R)-2-benzyl-1-oxo-3-phenyl-1,2,3,4-tetrahydro-isoquinolin-4-yl ester 

Relevant articles and documents

A New Route to Diarylisoquinolones

The lithium salts derived from position 3 of phthalides react with Schiff's bases to form a mixture of cis- and trans-2,3-disubstituted 4-hydroxy-3,4-dihydro-1(2H)-isoquinolones, the former isomer predominating.Acid-catalysed dehydration of the alcohols gives 2,4-disubstituted 1(2H)-isoquinolones, as a result of aryl group migration, whilst the cis-isomers, with methanesulphonyl chloride-pyridine as dehydrating agent, produce the 2,3-disubstituted 1(2H)-isoquinolones.