875272-89-2

Basic information

• Product Name: (S)-4-fluoro-4-Methyl-2-((S)-2,2,2-trifluoro-1-(4'-(Methylsulfonyl)biphenyl-4-yl)ethylaMino)pentanoic acid
• Synonyms: (S)-4-fluoro-4-Methyl-2-((S)-2,2,2-trifluoro-1-(4'-(Methylsulfonyl)biphenyl-4-yl)ethylaMino)pentanoic acid;(S)-4-fluoro-4-methyl-2-(((S)-2,2,2-trifluoro-1-(4-(methylsulfonyl)-[1,1-biphenyl]-4-yl)ethyl)amino)pentanoic acid
• CAS NO: 875272-89-2
• Molecular Formula: C₂₁H₂₃F₄NO₄S
• Molecular Weight: 461.4702328
• Mol File: 875272-89-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (S)-4-fluoro-4-Methyl-2-((S)-2,2,2-trifluoro-1-(4'-(Methylsulfonyl)biphenyl-4-yl)ethylaMino)pentanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-4-fluoro-4-Methyl-2-((S)-2,2,2-trifluoro-1-(4'-(Methylsulfonyl)biphenyl-4-yl)ethylaMino)pentanoic acid(875272-89-2)
• EPA Substance Registry System: (S)-4-fluoro-4-Methyl-2-((S)-2,2,2-trifluoro-1-(4'-(Methylsulfonyl)biphenyl-4-yl)ethylaMino)pentanoic acid(875272-89-2)

Safety Data

• Hazardous Substances Data: 875272-89-2(Hazardous Substances Data)

Usage

General Description

(S)-4-fluoro-4-Methyl-2-((S)-2,2,2-trifluoro-1-(4'-(Methylsulfonyl)biphenyl-4-yl)ethylaMino)pentanoic acid is a chemical compound with a complex structure. It consists of a fluoro-substituted methyl group, a trifluoroethylamino group, and a pentanoic acid moiety. The presence of a biphenyl-4-yl group with a methylsulfonyl substituent adds further complexity to the molecule. The combination of these chemical groups makes this compound potentially useful for various applications, including in the pharmaceutical industry for the development of new drugs. Its specific properties and potential uses would need to be further studied and evaluated.

Upstream product

• 893407-18-6 2,2,2-trifluoro-1-(4‘-(methylsulfonyl)-[1,1'-biphenyl]-4-yl)ethanone 
• 25895-60-7 sodium cyanoborohydride 
• 848949-85-9 ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate sulfate salt 
• 92-86-4 4-(4-bromophenyl)bromobenzene 
• 16184-89-7 4'-bromo-2,2,2-trifluoroacetophenone 
• 3393-00-8 (4’-bromo-[1,1’-biphenyl]-4-yl)(methyl)sulfane 
• 1004294-77-2 2,2,2-trifluoro-1-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)ethan-1-one 
• 2095926-24-0 (S)-ethyl 2-amino-4-fluoro-4-methylpentanoate hydrochloride 
• 893407-15-3 2,2,2-trifluoro-1-(4‘-(methylthio)-[1,1‘-biphenyl]-4-yl)ethanone 
• 589-87-7 1,4-bromoiodobenzene 
• 98546-51-1 (4-thiomethoxyphenyl)boronic acid 

Downstream Products

• 1064076-86-3 (2S)-4-fluoro-4-methyl-2-({(1S)-2,2,2-trifluoro-1-[4'-(methylsulfonyl)biphenyl-4-yl]ethyl}amino)pentanoic acid dicyclohexylamine salt 

Relevant articles and documents

CATHEPSIN INHIBITORS

This invention relates to compounds that are useful as inhibitors, in particular as inhibitors of Cathepsin K (CatK), and to a method of inhibiting cathepsin activity, comprising administering a compound or formulation comprising a compound according to the invention.

Preparation method of odanacatib, and preparation method of odanacatib intermediate

The invention discloses a preparation method of odanacatib, and a preparation method of an odanacatib intermediate. The preparation method of the trifluoroethylketone biphenyl methylsulfone intermediate I comprises the following step: 2,2,2-trifluoro-1-[4

Diastereoselective reductive amination process

This invention describes a reductive amination process whereby perfluorinated ketones or ketals are combined with α-aminoesters under basic conditions to form metal carboxylates. Diastereoselective reductions of the metal carboxylates enable access to two