87533-31-1Relevant academic research and scientific papers
Bis(N-amidinohydrazones) and N-(amidino)-N′-aryl-bishydrazones: New classes of antibacterial/antifungal agents
Shrestha, Sanjib K.,Kril, Liliia M.,Green, Keith D.,Kwiatkowski, Stefan,Sviripa, Vitaliy M.,Nickell, Justin R.,Dwoskin, Linda P.,Watt, David S.,Garneau-Tsodikova, Sylvie
, p. 58 - 66 (2017)
The emergence of multidrug-resistant bacterial and fungal strains poses a threat to human health that requires the design and synthesis of new classes of antimicrobial agents. We evaluated bis(N-amidinohydrazones) and N-(amidino)-N′-aryl-bishydrazones for
AMINOGUANIDINE HYDRAZONES AS RETROMER STABILIZERS USEFUL FOR TREATING NEUROLOGICAL DISEASES
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Page/Page column 46; 66, (2020/10/20)
The present invention relates to novel aminoguanidine hydrazone-derivatives of Formula (I) which are effective as retromer stabilizers and useful as neuroprotecting drugs. The invention also relates to pharmaceutical compositions comprising the compounds and their use in therapy and diagnostic.
Trypanocidal 1,3-Arylene Diketone Bis(guanylhydrazone)s. Structure-Activity Relationships among Substituted and Heterocyclic Analogues
Ulrich, Peter,Cerami, Anthony
, p. 35 - 40 (2007/10/02)
Based on the antitrypanosomal activity of 1,3-diacetylbenzene bis(guanylhydrazone) (4) and 2,6-diacetylpyridine bis(guanylhydrazone (17), a number of substituted and heterocyclic 1,3-arylene diketone bis(guanylhydrazone)s were prepared and tested against
