87533-54-8Relevant academic research and scientific papers
Linker-Region Modified Derivatives of the Deoxyhypusine Synthase Inhibitor CNI-1493 Suppress HIV-1 Replication
Schr?der, Marcus,Kolodzik, Adrian,Windshügel, Bj?rn,Krepstakies, Marcel,Priyadarshini, Poornima,Hartjen, Philip,Van Lunzen, Jan,Rarey, Matthias,Hauber, Joachim,Meier, Chris
, p. 91 - 103 (2016/02/09)
The inhibition of cellular factors that are involved in viral replication may be an important alternative to the commonly used strategy of targeting viral enzymes. The guanylhydrazone CNI-1493, a potent inhibitor of the deoxyhypusine synthase (DHS), preve
Trypanocidal 1,3-Arylene Diketone Bis(guanylhydrazone)s. Structure-Activity Relationships among Substituted and Heterocyclic Analogues
Ulrich, Peter,Cerami, Anthony
, p. 35 - 40 (2007/10/02)
Based on the antitrypanosomal activity of 1,3-diacetylbenzene bis(guanylhydrazone) (4) and 2,6-diacetylpyridine bis(guanylhydrazone (17), a number of substituted and heterocyclic 1,3-arylene diketone bis(guanylhydrazone)s were prepared and tested against
