875415-47-7Relevant articles and documents
Discovery of a potent and dissociated non-steroidal glucocorticoid receptor agonist containing an alkyl carbinol pharmacophore
Razavi, Hossein,Riether, Doris,Harcken, Christian,Bentzien, J?rg,Dinallo, Roger M.,Souza, Donald,Nelson, Richard M.,Kukulka, Alison,Fadra-Khan, Tazmeen N.,Pack Jr., Edward J.,Zuvela-Jelaska, Ljiljana,Pelletier, Josephine,Panzenbeck, Mark,Torcellini, Carol A.,Proudfoot, John R.,Nabozny, Gerald H.,Thomson, David S.
, p. 1934 - 1940 (2014/04/17)
Synthesis and structure-activity relationship (SAR) of a series of alkyl and cycloalkyl containing non-steroidal dissociated glucocorticoid receptor (GR) agonists is reported. This series of compounds was identified as part of an effort to replace the CF