875439-73-9Relevant academic research and scientific papers
Chemoenzymatic approaches toward dechloroansamitocin P-3
Meyer, Axel,Bruenjes, Marco,Taft, Florian,Frenzel, Thomas,Sasse, Florenz,Kirschning, Andreas
, p. 1489 - 1492 (2008/02/03)
Equation Presented The enantioselective total synthesis of proansamitocin, a key biosynthetic intermediate of the highly potent antitumor agent ansamitocin P-3, is described which bears a diene-ene RCM as the key macrocyclization step. Feeding of proansam
Synthesis of the N-acetylcysteamine thioester of seco-proansamitocin
Frenzel, Thomas,Bruenjes, Marco,Quitschalle, Monika,Kirschning, Andreas
, p. 135 - 138 (2007/10/03)
(Chemical Equation Presented) The enantioselective total synthesis of the N-acetylcysteamine thioester of seco-proansamitocin, a key biosynthetic intermediate of the highly potent antitumor agent ansamitocin, is described, which twice utilizes the Nagao a
