875439-75-1

Upstream product

• 875439-74-0 (E)-(3S,6S)-3-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-1-((R)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-4,6-dimethyl-hept-4-en-1-one 
• 875439-62-6 (3S,4E,6S)-7-(tert-butyldiphenylsilyloxy)-3-hydroxy-1-((4S)-4-isopropyl-2-thioxothiazolidin-3-yl)-4,6-dimethylhept-4-en-1-one 
• 144604-72-8 (4S,2E)-5-(tert-butyldiphenylsilyloxy)-2,4-dimethylpent-2-en-1-ol 
• 142592-66-3 ethyl (2E,4S)-5-(tert-butyldiphenylsilyloxy)-2,4-dimethylpent-2-enoate 
• 165258-10-6 (4S,2E)-5-(tert-butyldiphenylsilyloxy)-2,4-dimethylpent-2-enal 

Downstream Products

• 875439-83-1 3,7-bis-(tert-butyl-dimethyl-silanyloxy)-10-methoxy-4,6,14-trimethyl-9-oxo-15-[3-(2-trimethylsilanyl-ethoxycarbonylamino)-5-(2-trimethylsilanyl-ethoxycarbonyloxy)-phenyl]-pentadeca-4,11,13-trienethioic acid S-(2-acetylamino-ethyl) ester 
• 875439-82-0 (4E,11E,13E)-(3S,6S,7S,10R)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-10-methoxy-4,6,14-trimethyl-9-oxo-15-[3-(2-trimethylsilanyl-ethoxycarbonylamino)-5-(2-trimethylsilanyl-ethoxycarbonyloxy)-phenyl]-pentadeca-4,11,13-trienoic acid 
• 875439-68-2 Carbonic acid 3-[(2E,4E,11E)-(6R,7R,9S,10S,13S)-9,13-bis-(tert-butyl-dimethyl-silanyloxy)-7,15-dihydroxy-6-methoxy-2,10,12-trimethyl-pentadeca-2,4,11-trienyl]-5-(2-trimethylsilanyl-ethoxycarbonylamino)-phenyl ester 2-trimethylsilanyl-ethyl ester 
• 875439-81-9 Carbonic acid 3-[(2E,4E,11E)-(6R,9S,10S,13S)-9,13-bis-(tert-butyl-dimethyl-silanyloxy)-6-methoxy-2,10,12-trimethyl-7,15-dioxo-pentadeca-2,4,11-trienyl]-5-(2-trimethylsilanyl-ethoxycarbonylamino)-phenyl ester 2-trimethylsilanyl-ethyl ester 
• 875439-84-2 (4E,11E,13E)-(3S,6S,7S,10R)-3,7-Dihydroxy-10-methoxy-4,6,14-trimethyl-9-oxo-15-[3-(2-trimethylsilanyl-ethoxycarbonylamino)-5-(2-trimethylsilanyl-ethoxycarbonyloxy)-phenyl]-pentadeca-4,11,13-trienethioic acid S-(2-acetylamino-ethyl) ester 
• 875439-66-0 (E)-(3R,4R,6S,7S,10S)-6,10-Bis-(tert-butyl-dimethyl-silanyloxy)-3-methoxy-12-(4-methoxy-benzyloxy)-7,9-dimethyl-dodeca-1,8-dien-4-ol 
• 875439-64-8 (E)-(3S,4S,7S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-1-((R)-4-isopropyl-2-thioxo-thiazolidin-3-yl)-9-(4-methoxy-benzyloxy)-4,6-dimethyl-non-5-en-1-one 
• 875439-79-5 (E)-(3S,4S,7S)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-9-(4-methoxy-benzyloxy)-4,6-dimethyl-non-5-enoic acid methoxy-methyl-amide 
• 875439-65-9 (E)-(3S,4S,7S)-3,7-Bis-(tert-butyl-dimethyl-silanyloxy)-9-(4-methoxy-benzyloxy)-4,6-dimethyl-non-5-enal 
• 875439-78-4 (E)-(3S,4S,7S)-7-(tert-Butyl-dimethyl-silanyloxy)-3-hydroxy-9-(4-methoxy-benzyloxy)-4,6-dimethyl-non-5-enoic acid methoxy-methyl-amide 
• 875439-63-7 (2S,3E,5S)-5-(tert-butyldimethylsilyloxy)-7-(4-methoxybenzyloxy)-2,4-dimethylhept-3-en-1ol 
• 875439-77-3 (2S,3E,5S)-5-(tert-butyldimethylsilyloxy)-7-(4-methoxybenzyloxy)-2,4-dimethylhept-3-enal 
• 875439-76-2 (3S,4E,6S)-3-(tert-butyldimethylsilyloxy)-7-(tert-butyldiphenylsilyloxy)-4,6-dimethylhept-4-en-1-yl-para-methoxybenzyl ether 

Relevant academic research and scientific papers

Synthesis of the N-acetylcysteamine thioester of seco-proansamitocin

(Chemical Equation Presented) The enantioselective total synthesis of the N-acetylcysteamine thioester of seco-proansamitocin, a key biosynthetic intermediate of the highly potent antitumor agent ansamitocin, is described, which twice utilizes the Nagao a