875557-13-4

Basic information

• Product Name: Benzoic acid, 3-[[(3-pyridinylcarbonyl)amino]methyl]-, hydrazide
• CAS NO: 875557-13-4
• Molecular Formula: C14H14N4O2
• Molecular Weight: 270.291
• Mol File: 875557-13-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 3-[[(3-pyridinylcarbonyl)amino]methyl]-, hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 3-[[(3-pyridinylcarbonyl)amino]methyl]-, hydrazide(875557-13-4)
• EPA Substance Registry System: Benzoic acid, 3-[[(3-pyridinylcarbonyl)amino]methyl]-, hydrazide(875557-13-4)

Safety Data

• Hazardous Substances Data: 875557-13-4(Hazardous Substances Data)

Upstream product

• 264137-20-4 3-{[(pyridine-3-carbonyl)-amino]-methyl}-benzoic acid 
• 98-92-0 nicotinamide 
• 3569-99-1 N-hydroxymethylnicotinamide 

Downstream Products

• 875557-19-0 N-{3-[1-Phenyl-meth-(E)-ylidene-hydrazinocarbonyl]-benzyl}-nicotinamide 

Relevant articles and documents

Synthesis, characterization and biological activity of 1,3,4-substituted 2-azetidinones

Amido/imido alcohol/2-phenyl-3-hydroxyethylquinazolin-4 (3H) -one 1 on treatment with benzoic acid in the presence of cone. H2SO4 yields m-(aralkylamido/imidoalkyl/2-phenyl-3-ethyl-3H-4-oxoquinazolinyl) benzoic acids 2. The acid chloride of 2 on reaction with hydrazine hydrate affords m-(aralkylamido/imidoalkyl/2-phenyl-3-ethyl-3H-4-oxo-quinazolinyl) benzoic acid hydrazides 4 which on condensation with an aromatic aldehyde in acetic acid gives m-(aralkylamido/imidoalkyl/2-phenyl-3-ethyl-3H-4-oxo- quinazolinyl) benzoic acid hydrazones 5. Compounds 5 undergo cyclization with phenoxy acetic acid in the presence of thionyl chloride in dry benzene to furnish 1-[m-(aralkylamido/imidoalkyl/2-phenyl-3-ethyl-3H-4-oxo-quinazolinyl- benzamido)]-3-phenoxy-4-phenyl-2-azetidinones 6. The antiviral and antifungal activities of 6 have been reported.