87565-98-8

Usage

Uses

Used in Pharmaceutical Synthesis:
3-hydrazinobenzoic acid hydrochloride is used as a reagent for the synthesis of heterocyclic compounds, which are essential in the development of various drugs. Its presence in the synthesis process contributes to the creation of new pharmaceutical agents with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 3-hydrazinobenzoic acid hydrochloride is used as a building block in the production of various agrochemicals. Its role in this industry is crucial for the development of compounds that can protect crops and enhance agricultural productivity.
Used in Cancer Treatment Research:
3-hydrazinobenzoic acid hydrochloride is studied for its potential applications in the treatment of cancer due to its ability to inhibit certain enzymes and pathways associated with cell proliferation and survival. This makes it a valuable compound in the search for new therapeutic approaches to combat cancer.
Used in Medicinal Research:
Beyond its direct applications, 3-hydrazinobenzoic acid hydrochloride is a valuable asset in medicinal research. Its versatile properties allow for exploration in various areas of medicine, including the development of new drugs and therapies for a range of diseases.

InChI:InChI=1/C7H8N2O2.ClH/c8-9-6-3-1-2-5(4-6)7(10)11;/h1-4,9H,8H2,(H,10,11);1H

Upstream product

• 99-05-8 meta-aminobenzoic acid 

Downstream Products

• 725685-92-7 3-(5-amino-3-tert-butyl-pyrazol-1-yl)-benzoic acid ethyl ester 
• 725685-93-8 3-(5-amino-3-t-butyl-pyrazol-1-yl)benzoic acid 
• 312531-88-7 3-(3,5-dimethyl-1H-pyrazol-1-yl)benzoic acid 
• 1400633-26-2 3-(3-tert-butyl-5-(4-chlorophenyl)-4,5-dihydro-1H-pyrazol-1-yl)benzoic acid 
• 65-85-0 benzoic acid 

Relevant academic research and scientific papers

Anti-inflammatory medicaments

Novel compounds and methods of using those compounds for the treatment of inflammatory conditions are provided. In a preferred embodiment, modulation of the activation state of p38 kinase protein comprises the step of contacting the kinase protein with the novel compounds.

MODULATION OF PROTEIN FUNCTIONALITIES

New methods for the rational identification of molecules capable of interacting with specific naturally occurring proteins are provided, in order to yield new pharmacologically important compounds and treatment modalities. Broadly, the method comprises the steps of identifying a switch control ligand forming a part of a particular protein of interest, and also identifying a complemental switch control pocket forming a part of the protein and which interacts with said switch control ligand. The ligand interacts in vivo with the pocket to regulate the conformation and biological activity of the protein such that the protein assumes a first conformation and a first biological activity upon the ligand-pocket interaction, and assumes a second, different conformation and biological activity in the absence of the ligand-pocket interaction. Next, respective samples of said protein in the first and second conformations are provided, and these are screened against one or more candidate molecules by contacting the molecules and the samples. Thereupon, small molecules which bind with the protein at the region of the pocket may be identified. Novel protein-modulator adducts and methods of altering protein activity are also provided.

ENZYME MODULATORS AND TREATMENTS

Novel compounds and methods of using those compounds for the treatment of inflammatory conditions, hyperproliferative diseases, cancer, and diseases characterized by hypervascularization are provided. In a preferred embodiment, modulation of the activation state of p38 kinase protein ab1 kinase protein, bcr-ab1 kinase protein, braf kinase protein, VEGFR kinase protein, or PDGFR kinase protein comprises the step of contacting said kinase protein with the novel compounds.

Anti-inflammatory medicaments

Novel compounds and methods of using those compounds for the treatment of inflammatory conditions are provided. In a preferred embodiment, modulation of the activation state of p38 kinase protein comprises the step of contacting the kinase protein with the novel compounds.