875664-27-0

Basic information

• Product Name: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE
• Synonyms: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE;BUTTPARK 154\11-38;2-Amino-3-bromo-5-fluorobenzotrifluoride, 98%;Benzenamine,2-bromo-4-fluoro-6-(trifluoromethyl)-;2-Bromo-4-fluoro-6-(trifluoromethyl)benzenamine
• CAS NO: 875664-27-0
• Molecular Formula: C₇H₄BrF₄N
• Molecular Weight: 258.01
• Product Categories: Anilines, Aromatic Amines and Nitro Compounds
• Mol File: 875664-27-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 212.553 °C at 760 mmHg
• Flash Point: 82.349 °C
• Appearance: /
• Density: 1.772 g/cm³
• Vapor Pressure: 0.172mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE(875664-27-0)
• EPA Substance Registry System: 2-BROMO-4-FLUORO-6-(TRIFLUOROMETHYL)ANILINE(875664-27-0)

Safety Data

• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: 6.1
• Hazardous Substances Data: 875664-27-0(Hazardous Substances Data)

Usage

General Description

2-Bromo-4-fluoro-6-(trifluoromethyl)aniline is a chemical compound often used in the field of organic synthesis. It is classified as an aromatic amine featuring a bromine, a fluorine, and a trifluoromethyl group attached to the aniline ring, which is essentially a benzene ring attached to an amine (-NH2) group. Its molecular formula is C7H4BrF4N, indicating it consists of seven carbon atoms, four hydrogen atoms, one bromine atom, four fluorine atoms, and one nitrogen atom. Like many chemical substances, it must be handled with care to prevent adverse health effects as it might be irritating to the eyes, skin, and respiratory system. It generally exists as a solid and is soluble in organic solvents. This chemical is typically stored in a cool, dry place for preservation. It's primarily used in research environments rather than in commercial or home environments.

InChI:InChI=1/C7H4BrF4N/c8-5-2-3(9)1-4(6(5)13)7(10,11)12/h1-2H,13H2

Upstream product

• 393-39-5 4-fluoro-2-(trifluoromethyl)aniline 

Downstream Products

• 1027511-90-5 1,2-dibromo-5-fluoro-3-(trifluoromethyl)benzene 
• 1027511-98-3 1-bromo-2-chloro-5-fluoro-3-(trifluoromethyl)benzene 

Relevant articles and documents

QUINOXALINE DERIVATIVES

The present invention relates to compounds according to general formula (I), which act as modulators of the glucocorticoid receptor and can be used in the treatment and/or prophylaxis of disorders which are at least partially mediated by the glucocorticoid receptor.

COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH NLRP ACTIVITY

In one aspect, compounds of Formula AA, or a pharmaceutically acceptable salt thereof, are featured. The variables shown in Formula AA are as defined in the claims. The compounds of formula AA are NLRP3 activity modulators and, as such, can be used in the treatment of metabolic disorders (e.g. Type 2 diabetes, atherosclerosis, obesity or gout), a disease of the central nervous system (e.g. Alzheimer's disease, multiple sclerosis, Amyotrophic Lateral Sclerosis or Parkinson's disease), lung disease (e.g. asthma, COPD or pulmonary idiopathic fibrosis), liver disease (e.g. NASH syndrome, viral hepatitis or cirrhosis), pancreatic disease (e.g. acute pancreatitis or chronic pancreatitis), kidney disease (e.g. acute kidney injury or chronic kidney injury), intestinal disease (e.g. Crohn's disease or Ulcerative Colitis), skin disease (e.g. psoriasis), musculoskeletal disease (e.g. scleroderma), a vessel disorder (e.g. giant cell arteritis), a disorder of the bones (e.g. osteoarthritis, osteoporosis or osteopetrosis disorders), eye disease (e.g. glaucoma or macular degeneration), a disease caused by viral infection (e.g. HIV or AIDS), an autoimmune disease (e.g. Rheumatoid Arthritis, Systemic Lupus Erythematosus or Autoimmune Thyroiditis), cancer or aging.