87571-88-8 Usage
General Description
Endo-3-Aminotropane, also known as norpseudoephedrine, is a chemical compound that belongs to the class of amines. It is a psychoactive drug and is commonly used as a stimulant and anorectic agent. Endo-3-Aminotropane acts as a norepinephrine-dopamine releasing agent and inhibits the reuptake of these neurotransmitters, leading to increased levels of dopamine and norepinephrine in the brain. This results in enhanced mood, arousal, and energy levels. It also has appetite-suppressant effects, making it popular for use as a weight-loss aid. Endo-3-Aminotropane has been implicated in cases of illicit drug use and misuse, and its use is regulated in many countries due to its potential for abuse and addiction.
Check Digit Verification of cas no
The CAS Registry Mumber 87571-88-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,5,7 and 1 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 87571-88:
(7*8)+(6*7)+(5*5)+(4*7)+(3*1)+(2*8)+(1*8)=178
178 % 10 = 8
So 87571-88-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H16N2/c1-10-7-2-3-8(10)5-6(9)4-7/h6-8H,2-5,9H2,1H3/t6-,7+,8-
87571-88-8Relevant articles and documents
A practical synthesis of 7-azaindolylcarboxy-endo-tropanamide (DF 1012)
Allegretti, Marcello,Anacardio, Roberto,Cesta, M. Candida,Curti, Roberto,Mantovanini, Marco,Nano, Giuseppe,Topai, Alessandra,Zampella, Giuseppe
, p. 209 - 213 (2013/09/05)
An optimised cost-effective synthesis of the new antitussive drug, DF1012, is herewith reported. The new synthetic route to the key intermediate DF1005 is based on the unusual deprotection step of the 1-tert-butyl-3-cyano-7-azaindole intermediate, which can also be regarded as a convenient way for the industrial production of the expensive 7-azaindole 1. The second key intermediate, endo-tropanamine 6, was obtained in high yield by a novel one-pot stereoselective process using a Pd-catalysed reductive amination procedure.