87573-88-4

Usage

Organic compound

Yes

Class

Pyrimidinones

Acetyl group presence

Yes (enhances reactivity)

Pharmaceutical industry applications

Potential (intermediate in drug synthesis)

Organic synthesis uses

Preparation of other chemical compounds

Potential uses

Wide range of industries and chemical processes

Upstream product

• 87573-83-9 5-acetyl-2-methylsulphonylpyrimidine 
• 84755-29-3 1-(2-(methylthio)pyrimidin-5-yl)ethanone 
• 110100-00-0 1-(2-chloropyrimidin-5-yl)ethan-1-one 

Downstream Products

• 110100-06-6 5-acetyl-1-benzyl-2(1H)-pyrimidinone 

Relevant academic research and scientific papers

Organomanganese(II) Reagents in the Synthesis of 5-Pyrimidinyl Ketones

Substituted alkyl 5-pyrimidinyl ketones were formed from acid chlorides of pyrimidine-5-carboxylic acids and alkylmanganese(II) iodides.The corresponding alcohols were also formed in the case of sterically less requiring organomanganese reagents and the a

Syntheses and Reactions of Some 5-Vinyl- and 5-Ethynylpyrimidines

5-β,β-Dichlorovinyl- and 5-α-chlorovinylpyrimidines have been prepared from 5-acetyl-2-methylthiopyrimidines.HCl elimination from the 5-α-chlorovinyl derivatives yields the 5-ethynyl analogues.Peracid or chlorine oxidation of the sulfides yields the sulfones which may be hydrolyzed to the corresponding lactams.The reaction paths are discussed.