875782-99-3

Basic information

• Product Name: C₃₉H₄₄BrN₃O₄
• Synonyms: C₃₉H₄₄BrN₃O₄
• CAS NO: 875782-99-3
• Molecular Weight: 698.7
• Mol File: 875782-99-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₉H₄₄BrN₃O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₉H₄₄BrN₃O₄(875782-99-3)
• EPA Substance Registry System: C₃₉H₄₄BrN₃O₄(875782-99-3)

Safety Data

• Hazardous Substances Data: 875782-99-3(Hazardous Substances Data)

Upstream product

• 78551-60-7 1-benzyl-4-(tert-butyloxycarbonyl)piperazin-2-one 

Downstream Products

• 875783-31-6 C₄₈H₆₁N₅O₆ 
• 875783-28-1 C₄₅H₄₉N₃O₄ 

Relevant articles and documents

SUBSTITUTED AMIDE BETA SECRETASE INHIBITORS

Disclosed are novel compounds of the formula (I) or a pharmaceutically acceptable salt or solvate thereof, wherein R1, R2, R3, R4 and X are as defined in the specification. Also disclosed are pharmaceutical compositions comprising the compounds of formula (I). Also disclosed are methods of treating cognitive or neurodegenerative diseases such as Alzheimer's disease. Also disclosed are methods of treating a cognitive or neurodegenerative disease comprising administering to a patient I need of such treatment a combination of at least one compound of formula (I) and at least one compound selected from the group consisting of β-secretase inhibitors other than those of formula (I), HMG-CoA reductase inhibitors, gamma-secretase inhibitors, non-steroidal anti-inflammatory agents, N-methyl-D-aspartate receptor antagonists, cholinesterase inhibitors and anti-amyloid antibodies.