875811-94-2Relevant academic research and scientific papers
Synthesis, conformation, and stereodynamics of a salt of 2-{[2-(3,4-dichlorophenyl)-ethyl]propylamino}-1-pyridin-3-ylethanol
Korosec, Tina,Grdadolnik, Joze,Urleb, Uros,Kocjan, Darko,Grdadolnik, Simona Golic
, p. 792 - 795 (2006)
A novel synthetic route was developed for 2-{[2-(3,4-dichlorophenyl)ethyl] propylamino}-1-pyridin-3-ylethanol (4). A dynamic process due to nitrogen inversion at the central amine nitrogen has been identified by NMR spectroscopy for the dihydrobromide sal
Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14α-demethylase (CYP51)
Korosec, Tina,Acimovic, Jure,Seliskar, Matej,Kocjan, Darko,Tacer, Klementina Fon,Rozman, Damjana,Urleb, Uros
, p. 209 - 221 (2008/04/12)
Novel cholesterol biosynthesis inhibitors, a group of pyridylethanol(phenylethyl)amine derivatives, were synthesized. Sterol profiling assay in the human hepatoma HepG2 cells revealed that compounds target human lanosterol 14α-demethylase (CYP51). Structu
