87582-33-0 Usage
Physical State
Yellow water-soluble tetrazolium dye
Function
Used to measure cell viability and proliferation in biological research
Mechanism of Action
MTT is reduced by mitochondrial dehydrogenases in living cells to form a purple formazan product
Quantification Method
The purple formazan product can be quantified spectrophotometrically
Purpose
Allows researchers to assess the metabolic activity and health of cells
Applications
Commonly used in cell culture assays to evaluate the effectiveness of drugs, toxins, and other experimental treatments on cell viability
Additional Uses
Utilized in the development of in vitro toxicology and drug screening assays for medical and pharmaceutical research
Check Digit Verification of cas no
The CAS Registry Mumber 87582-33-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,7,5,8 and 2 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 87582-33:
(7*8)+(6*7)+(5*5)+(4*8)+(3*2)+(2*3)+(1*3)=170
170 % 10 = 0
So 87582-33-0 is a valid CAS Registry Number.
InChI:InChI=1/C21H17N5/c1-3-9-16(10-4-1)23-25-21(26-24-17-11-5-2-6-12-17)19-15-22-20-14-8-7-13-18(19)20/h1-15,23,25H/b21-19+,26-24+
87582-33-0Relevant academic research and scientific papers
Synthesis and antifertility activity of 1,5-diaryl-3-(3'-indolyl)formazans
Kidwai,Negi,Gupta
, p. 2363 - 2364 (2007/10/02)
The synthesis and antifertility of 1,5-diary-3-(3'-indolyl)formazans with a substituted aryl group (2-8) are described
Newer formazans and tetrazolium indoles as potential CNS-active agents
Sathi,Gujrati,Nath,Agarwal,Bhargava,Shanker
, p. 1218 - 1221 (2007/10/02)
Some new 2-aryl-5-(3'-indole)-3'-substituted phenyl tetrazolium bromide/iodide salts (IV) were synthesized by the oxidation of 1-aryl-3-(3'-indole)-5-substituted phenyl formazans (III). These compounds III and IV were evaluated for their monoamine oxidase
