875877-88-6Relevant academic research and scientific papers
Reactivity of 3-silyloxy-1,4-enynes: Gold(III)-catalyzed regioselective nucleophilic substitution
Haug, Timm T.,Harschneck, Tobias,Duschek, Alexander,Lee, Chang-Uk,Binder, J?rg T.,Menz, Helge,Kirsch, Stefan F.
experimental part, p. 510 - 514 (2009/06/05)
Gold-catalyzed reactions of 3-silyloxy-1,4-enynes with alcohols afford primary, secondary, and tertiary pent-2-en-4-ynyl ethers in moderate to excellent yields. The substitution proceeds with high regioselectivity. An initial cyclization providing five-me
Siloxyallenes revisited. A useful functional intermediate for the synthesis of (Z)-β-branched Morita-Baylis-Hillman type adducts and (Z)-chalcones
Yoshizawa, Kazuhiro,Shioiri, Takayuki
, p. 6259 - 6286 (2008/02/04)
Siloxyallenes proved to be a useful functional intermediate in the preparation of (Z)-β-branched Morita-Baylis-Hillman type adducts by the reaction of aldehydes with silylacetylenes or siloxypropynes. Various (Z)-chalcones were stereoselectively synthesized from siloxypropynes via siloxyallenes.
Synthesis of β-branched Morita-Baylis-Hillman-type adducts from 1,3-diaryl-2-propynyl trimethylsilyl ethers and aldehydes catalyzed by potassium tert-butoxide
Yoshizawa, Kazuhiro,Shioiri, Takayuki
, p. 757 - 761 (2007/10/03)
1,3-Diaryl-2-propynyl trimethylsilyl ethers were easy to isomerize into the corresponding siloxyallenes using a catalytic amount of potassium tert-butoxide under very mild conditions. The siloxyallenes reacted in situ with various aldehydes to afford Z-selective β-branched Morita-Baylis-Hillman-type adducts in a one-pot reaction after acid treatment.
