875930-15-7

Basic information

• Product Name: Benzenamine, 4-fluoro-2-(phenylethynyl)-
• CAS NO: 875930-15-7
• Molecular Formula: C14H10FN
• Molecular Weight: 211.239
• Mol File: 875930-15-7.mol
• Article Data: 41

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-fluoro-2-(phenylethynyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-fluoro-2-(phenylethynyl)-(875930-15-7)
• EPA Substance Registry System: Benzenamine, 4-fluoro-2-(phenylethynyl)-(875930-15-7)

Safety Data

• Hazardous Substances Data: 875930-15-7(Hazardous Substances Data)

Upstream product

• 61272-76-2 4-fluoro-2-iodoaniline 
• 536-74-3 phenylacetylene 
• 1003-98-1 2-bromo-4-fluoroaniline 
• 371-40-4 4-fluoroaniline 

Downstream Products

• 946162-00-1 4-methyl-N-(4-fluoro-2-phenylethynyl-phenyl)-benzenesulfonamide 
• 1221167-71-0 C₂₂H₁₇FN₂OS 
• 1429782-42-2 (Z)-4-benzylidene-6-fluoro-4H-benzo[d][1,3]thiazine-2-thiol 
• 1421753-37-8 (Z)-4-benzylidene-6-fluoro-1,4-dihydro-2H-3,1-benzoxazine-2-one 
• 1415332-61-4 5-fluoro-1-(5-methyl-2-phenyl-1-tosyl-1H-indol-4-yl)-2-phenyl-1H-indole 

Relevant articles and documents

Copper-Catalyzed Aerobic Oxidative Cyclization of 2-Alkynylanilines with Nitrosoarenes: Synthesis of Organic Solid Mechanoluminescence Compounds of 4-Oxo-4 H-cinnolin-2-ium-1-ide

An efficient Cu(I)/DMAP/air system for the one-pot synthesis of 4-oxo-4H-cinnolin-2-ium-1-ides, which are often difficult to prepare by traditional routes from substituted 2-alkynylanilines and nitrosoarenes, was developed. These 4-oxo-4H-cinnolin-2-ium-1-ides have practical applications as mechanoluminescent materials. Preliminary mechanistic experiments were performed, and a plausible mechanism for this tandem process is proposed. The use of an inexpensive copper catalyst and molecular oxygen as the oxygen source and the oxidant make this an attractive green protocol with potential synthetic applications.

Copper(I)-Mediated Cascade Annulation via Dual C-H/C-H Activation: Access to Benzo[a]carbazolic AEEgens

A Cu(I)-mediated cascade cyclization/annulation of unprotectedo-alkynylanilines with maleimides in one pot is developed. The protocol offers sequential formation of one C-N and two C-C bonds to deliver fused benzo[a]carbazoles having free NH skeletons. The annulated products display fluorescence emission in the range of 485-502 nm with a large Stokes shift and fluorescence lifetime of ～17 ns. The annulated3aadisplays AEE behavior in the ethanol/hexane system and possesses marigold-flower-like morphology at the aggregated state. Cell viability assays enumerate biocompatible AEEgens, while their high intracellular fluorescence depicts cell imaging applicability.

Nickel-Catalyzed Arylative Additions on 2-Alkynyl-N-Arylsulfonylanilides to Construct Functionalized Indoles

The addition of aryl iodides to 2-alkynyl-N-sulfonylanilides to form 2,3-difunctionalized N-arylsulfonylindoles can be catalyzed using a nickel catalyst ligated to a bis(cyclohexanyl)phosphinoferrocene. A variety of nickel complexes can be used as precata