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Usage

Uses

Used in Pharmaceutical Synthesis:
1-phenyl-1H-pyrazol-5-ol is used as a key intermediate in the synthesis of pharmaceuticals for its ability to inhibit cyclin-dependent kinases, which are crucial in cell cycle regulation and have implications in the development of cancer and other diseases.
Used in Drug Development:
1-phenyl-1H-pyrazol-5-ol is utilized as a potential drug candidate due to its anti-inflammatory and antioxidant properties, which are beneficial in treating a variety of inflammatory conditions and oxidative stress-related disorders.
Used in Organic Chemistry Research:
1-phenyl-1H-pyrazol-5-ol is employed as a subject of ongoing research in the field of organic chemistry, where its unique structure and properties are explored for the development of new materials and applications.
Used in Cyclin-Dependent Kinase Inhibition:
1-phenyl-1H-pyrazol-5-ol is used as a selective and potent inhibitor of cyclin-dependent kinases, playing a crucial role in the regulation of the cell cycle and offering therapeutic potential in the treatment of cancer and other cell cycle-related diseases.
Used in Anti-Inflammatory and Antioxidant Therapies:
1-phenyl-1H-pyrazol-5-ol is applied as an agent with anti-inflammatory and antioxidant capabilities, making it suitable for the development of treatments aimed at reducing inflammation and oxidative stress in various medical conditions.

Upstream product

• 34846-90-7 methyl 3-methoxyprop-2-enoate 
• 100-63-0 phenylhydrazine 

Downstream Products

• 590410-64-3 (5-hydroxy-1-phenyl-1H-pyrazol-4-yl)(phenyl)methanone 
• 900810-56-2 4-benzoyl-1-phenyl-1,2-dihydropyrazol-5-one 
• 635288-51-6 1-(5-hydroxy-1-phenyl-1H-pyrazol-4-yl)-3-phenylpropane-1,3-dione 
• 900810-60-8 (5-oxiranylmethoxy-1-phenyl-1H-pyrazol-4-yl)phenylmethanone 
• 22717-34-6 1,2-dihydro-1-methyl-2-phenyl-3H-pyrazol-3-one 
• 748159-01-5 (5-hydroxy-1-phenyl-1H-pyrazol-4-yl)(2-thienyl)methanone 
• 635288-46-9 (E)-1-(5-hydroxy-1-phenyl-(1H)-pyrazole-4-yl)-3-phenylprop-2-ene-1-one 
• 635288-50-5 1-(5-hydroxy-1-phenyl-1H-pyrazol-4-yl)ethan-1-one 

Relevant academic research and scientific papers

1-aryl-5-hydroxy pyrazole of preparation method

The invention discloses a preparation method for 1-aryl-5-hydroxy pyrazol. According to the preparation method, the 1-aryl-5-hydroxy pyrazol is prepared by reaction of aryl hydrazine or hydrochloride of the aryl hydrazine and methoxy methyl acrylate in a solvent, and the chemical reaction formula is as shown in the specification. The preparation method for 1-aryl-5-hydroxy pyrazol is simple, has few reaction steps, is easy to operate, has the product yield greater than 50%, which is much higher than that of the prior art, uses the raw materials of wide source, and is applicable to industrial production.