87601-60-3Relevant academic research and scientific papers
CERTAIN 3-PHOSPHINYL-AMINO-2-OXO-1H-AZEPINE-1-ACETIC ACID DERIVATIVES HAVING ANTI-HYPERTENSIVE ACTIVITY
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, (2008/06/13)
Phosphonamide substituted lactams of the formula STR1 are disclosed. These compounds are useful as hypotensive agents.
PHOSPHORUS CONTAINING COMPOUNDS AND USE AS HYPOTENSIVES
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, (2008/06/13)
Phosphorus containing compounds of the formula STR1 wherein X is a substituted or unsubstituted imino or amino acid and A is STR2 These compounds possess angiotensin converting enzyme activity and are thus useful as hypertensive agents.
THIAZINE AND THIAZEPINE CONTAINING COMPOUNDS
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, (2008/06/13)
This invention is directed to compounds of the formula STR1 wherein X is a thiazine or thiazepine selected from STR2 These compounds possess angiotensin converting enzyme inhibition activity and are thus useful as hypotensive agents.
PREPARATION OF OPTICALLY ACTIVE 2-AMINOALKYLPHOSPHINIC AND PHOSPHONIC ACIDS
Duggan, Mark E.,Karanewsky, Donald S.
, p. 2935 - 2938 (2007/10/02)
The reaction of sodium alkylphosphinates or sodium dialkylphosphonates with tosylamino tosylates of amino alcohols derived from 1-aminoalkylcarboxylic acids gives high yields of optically active 2-tosylaminoalkylphosphinic or phosphonic esters.
ANIMATION REDUCTRICE DES β-CETOPHOSPHONATES: PREPARATION D'ACIDES AMINOALKYLPHOSPHONIQUES
Varlet, J. M.,Collignon, N.,Savignac, Ph.
, p. 3713 - 3721 (2007/10/02)
Diethyl 2-oxo-alkylphosphonates undergo reductive amination in the presence of an amine and sodium cyanohydridoborate (NaBH3CN) in MeOH at Ph 7-7.5.Studies with a large variety of ketophosphonates show that the reaction rate is very sensitive to steric hi
