876064-00-5Relevant academic research and scientific papers
Highly potent, orally available anti-inflammatory broad-spectrum chemokine inhibitors
Fox, David J.,Reckless, Jill,Lingard, Hannah,Warren, Stuart,Grainger, David J.
, p. 3591 - 3595 (2009)
A series of 3-acylaminocaprolactams are inhibitors of chemokine-induced chemotaxis. Branching of the side chain α-carbon provides highly potent inhibitors of a range of CC and CXC chemokines. The most potent compound has an ED50 of 40 pM. Selec
