876065-78-0

Upstream product

• 6630-33-7 ortho-bromobenzaldehyde 
• 6921-34-2 benzylmagnesium chloride 
• 574-98-1 2-(2-bromoethyl)isoindoline-1,3-dione 
• 876065-74-6 9b-benzyl-2,3-dihydrooxazolo[2,3-a]isoindol-5-(9bH)-one 
• 876065-75-7 3-benzyl-2-(2-hydroxyethyl)-2,3-dihydroisoindol-1-one 

Relevant academic research and scientific papers

Synthesis of benzazepinoisoindolinone and bridged tricyclic isoindolinone derivatives

N-(2,2-Diethoxyethyl)isoindolin-1-ones were readily obtained via the reaction of o-lithiated aromatic imines with carbon monoxide under mild conditions in gram-scale, and they were double-deprotonated by two equivalents of potassium bis(trimethylsilyl)ami

Oxidized isoquinolinoisoindolinone and benzazepinoisoindolinone alkaloids cores by convergent cyclisation processes: π-aromatic attack of thionium and oxonium species

An efficient methodology for synthesis of isoindoloisoquinoline 5a and isoindolobenzazepine 5b in oxidized forms as tetracyclic alkaloids cores are reported from N-bromoethylphthalimide (6) or phthalic anhydride and 2-phenylthioethylamine (8) in a five- o