876069-79-3Relevant academic research and scientific papers
Gold-catalyzed intramolecular regio- and enantioselective cycloisomerization of 1,1-bis(indolyl)-5-alkynes
Huang, Long,Yang, Hai-Bin,Zhang, Di-Han,Zhang, Zhen,Tang, Xiang-Ying,Xu, Qin,Shi, Min
, p. 6767 - 6771 (2013/07/25)
Bis(indole) alkaloids analogues were prepared under mild conditions and in high yields through a gold-catalyzed cycloisomerization of 1,1-bis(indolyl)-5- alkynes (see scheme). The enan Copyright
Cationic rhodium(I)/H8-binap complex catalyzed [2+2+2] cycloadditions of 1,6- And 1,7-diynes with carbonyl compounds
Otake, Yousuke,Tanaka, Rie,Tanaka, Ken
supporting information; experimental part, p. 2737 - 2747 (2009/08/09)
We have established that a cationic rhodium(I)/H8-binap complex catalyzes [2+2+2] cycloadditions of a variety of 1,6and 1,7-diynes with both electron-deficient and electron-rich carbonyl compounds, leading to dienones in high yield under mild reaction conditions. In the reactions with acyl phosphonates, the reactivity of 1,6- and 1,7-diynes was highly dependent on their own structures. The addition of chelating diethyl oxalate effectively promoted the [2+2+2] cycloadditions involving acyl phosphonates, presumably due to the equilibrium formation of the desired 1:1 rhodium complex of the diyne and the acyl phosphonate by facile ligand exchange between the diyne and weakly coordinated diethyl oxalate. In the reactions involving bifunctional carbonyl compounds or unsymmetrical 1,6-diynes, high chemo- or regioselectivities were observed. Wiley-VCH Verlag GmbH & Co. KGaA.
Palladium(0)-catalyzed alkylative cyclization of alkynals and alkynones: Remarkable trans-addition of organoboronic reagents
Tsukamoto, Hirokazu,Ueno, Tatsuhiko,Kondo, Yoshinori
, p. 1406 - 1407 (2007/10/03)
Palladium/monophosphine complexes catalyze trans-selective arylative, alkenylative, and alkylative cyclization reactions of alkynals and alkynones with organoboronic reagents. These reactions afford six-membered allylic alcohols with endo-tri- or tetrasub
