87627-22-3

Usage

Uses

Used in Flavor and Fragrance Industry:
(2-methyl-4-oxo-4H-chromen-8-yl)acetic acid is used as a flavoring agent for its vanilla-like scent, adding a pleasant aroma to various food products and beverages.
Used in Pharmaceutical Industry:
(2-methyl-4-oxo-4H-chromen-8-yl)acetic acid is used as a potential medicinal compound due to its anti-inflammatory properties, making it a candidate for the development of treatments for various diseases, including cancer.
Used in Cosmetic Industry:
(2-methyl-4-oxo-4H-chromen-8-yl)acetic acid is used as a fragrance ingredient in cosmetic products, leveraging its appealing scent to enhance the sensory experience of these products.

Upstream product

• 87627-21-2 8-cyanomethyl-2-methylchromone 
• 23287-26-5 3-methylsalicylic acid methyl ester 
• 7664-93-9 sulfuric acid 
• 138565-09-0 <1-(2-hydroxy-3-methylbenzoyl)methylene>triphenylphosphorane 
• 41796-14-9 2,8-dimethylchromone 
• 87165-87-5 8-bromomethyl-2-methylchromone 
• 365431-18-1 8-allyl-2-methyl-4H-chromen-4-one 
• 58621-39-9 2-acetyl-6-allylphenol 
• 365431-24-9 2-methylchromone-8-acetaldehyde 

Downstream Products

• 139374-23-5 {4-Oxo-2-[(E)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-4H-chromen-8-yl}-acetic acid 
• 139374-22-4 [4-Oxo-2-((E)-styryl)-4H-chromen-8-yl]-acetic acid 
• 139374-24-6 4-[(E)-2-(8-Carboxymethyl-4-oxo-4H-chromen-2-yl)-vinyl]-benzoic acid 

Relevant academic research and scientific papers

Synthesis of 2-methylchromone-8-acetic acids and 2-methyl-chromone-8-carboxylic acids

2-Hydroxy-3-allylacetophenones on Claisen condensation with EtOAc/Na gave intermediate diketone, followed by cyclization in AcOH/HCl gave 8-ally1/-1-propenylchromones, which on ozonolysis gave 8-acetaldehydes or 8-carboxaldehydes. The above aldehydes on oxidation with KMnO4 furnished corresponding 8-acetic acids and 8-carboxylic acids.

Heterocyclic compounds: 2-styryl-4H-1-benzopyran-4-ones

A compound of the formula (I) STR1 in which: R1 represents a hydrogen atom, a lower alkyl group, a hydroxy group or a lower alkoxy group, R2, R3, R4, R5, R6, R7, R8 an

A Convenient Synthesis of (2-Styrylchromon-8-yl)acetic Acids

(2-Styrylchromon-8-yl)acetic acid, structural analogs of (flavon-8-yl)acetic acid (FAA) have been synthesized with satisfactory yields according to two different methods.The 1H and 13C nmr data favor the S-trans stereoisomers.