876288-73-2

Upstream product

• 475641-60-2 (2R,4aR,6S,7R,9S,10aS)-6-(tert-Butyl-diphenyl-silanyloxymethyl)-9-methyl-2-phenyl-octahydro-1,3,5-trioxa-benzocycloocten-7-ol 
• 2746-25-0 p-Methoxybenzyl bromide 
• 876288-71-0 (2'R,3'S,5'R,7'S,8'R)-7'-(4-bromobenzyloxy)-8'-(4-bromobenzyloxymethyl)-2'-(tret-butyldimethylsilyloxymethyl)-5'-methyl-oxocan-3'-yl 2,2-dimethylpropionate 
• 876288-72-1 (2S,3R,5S,7S,8R)-7-(4-bromobenzyloxy)-8-(4-bromobenzyloxymethyl)-2-(tret-butyldimethylsilyloxymethyl)-5-methyl-oxocan-3-ol 
• 876288-69-6 (1'R,3'S,4'R,6'R,8'S,10'R)-3'-(tret-butyldimethylsilyloxymethyl)-6'-methyl-10'-phenyl-2',9',11'-trioxabicyclo[6.4.0]dodecan-4'-yl 2,2-dimethylpropionate 
• 876288-70-9 (2'R,3'S,5'R,7'S,8'R)-2'-(tret-butyldimethylsilyloxymethyl)-7'-hydroxy-8'-hydroxymethyl-5'-methyl-oxocan-3'-yl 2,2-dimethylpropionate 
• 909001-62-3 [(2S,3R,5R,7S,8R)-7-(4-Bromo-benzyloxy)-8-(4-bromo-benzyloxymethyl)-3-(4-methoxy-benzyloxy)-5-methyl-oxocan-2-ylmethoxy]-tert-butyl-diphenyl-silane 

Downstream Products

• 876288-74-3 (2R,3S,5S,7R,8S)-3-(4-Bromo-benzyloxy)-2-(4-bromo-benzyloxymethyl)-7-(4-methoxy-benzyloxy)-8-((E)-2-methoxy-vinyl)-5-methyl-oxocane 
• 876288-67-4 [(2S,3R,5S,7S,8R)-7-(4-Bromo-benzyloxy)-8-(4-bromo-benzyloxymethyl)-3-(4-methoxy-benzyloxy)-5-methyl-oxocan-2-yl]-acetaldehyde 
• 876288-89-0 2-[8-benzyloxy-9-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-yl]-1-[7-(4-bromo-benzyloxy)-6-(4-bromo-benzyloxymethyl)-3-hydroxy-2,9-dimethyl-decahydro-1,5-dioxa-benzocycloocten-2-yl]-ethanone 
• 876288-84-5 5-[8-benzyloxy-9-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-yl]-1-[7-(4-bromo-benzyloxy)-8-(4-bromo-benzyloxymethyl)-3-(4-methoxy-benzyloxy)-5-methyl-oxocan-2-yl]-3-methyl-pent-3-en-2-ol 
• 876288-83-4 5-[8-benzyloxy-9-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-yl]-1-[7-(4-bromo-benzyloxy)-8-(4-bromo-benzyloxymethyl)-3-(4-methoxy-benzyloxy)-5-methyl-oxocan-2-yl]-3-methyl-pent-3-en-2-ol 
• 876288-88-9 C₆₄H₉₀Br₂O₁₀Si₂ 
• 876288-85-6 1-{3-[8-benzyloxy-9-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-ylmethyl]-2-methyl-oxiranyl}-2-[7-(4-bromo-benzyloxy)-8-(4-bromo-benzyloxymethyl)-3-(4-methoxy-benzyloxy)-5-methyl-oxocan-2-yl]-ethanol 
• 876288-87-8 C₆₄H₉₂Br₂O₁₀Si₂ 
• 876288-66-3 2-(2-{3-[8-benzyloxy-9-benzyloxymethyl-3-(tert-butyl-dimethyl-silanyloxy)-2,3,4,7,8,9-hexahydro-oxonin-2-ylmethyl]-2-methyl-oxiranyl}-2-triethylsilanyloxy-ethyl)-7-(4-bromo-benzyloxy)-8-(4-bromo-benzyloxymethyl)-5-methyl-oxocan-3-ol 
• 876288-86-7 C₇₂H₁₀₀Br₂O₁₁Si₂ 

Relevant academic research and scientific papers

Synthesis of the common FGHI-ring part of ciguatoxins

The common FGHI-ring part (2) of ciguatoxins has been synthesized from the F- and I-ring parts (6 and 5, respectively). The Nozaki-Hiyama-Kishi coupling of 6 with 5 followed by regio- and stereoselective epoxidation at C29 and C30 afforded an epoxide (4),