87634-62-6Relevant academic research and scientific papers
Pd(ii)-Catalyzed alkyne annulation through allylic isomerization: synthesis of spiro-cyclopentadiene pyrazolones
Changmai, Sumi,Sultana, Sabera,Sarma, Bipul,Gogoi, Sanjib
supporting information, p. 6027 - 6030 (2021/06/21)
The Pd(ii)-catalyzed activation of Csp2-H bond and double alkyne annulation which proceedsviaallylic isomerization is reported for the first time. This reaction of antipyrines with alkynes provides an efficient synthetic route for the biologically important spiro-cyclopentadiene pyrazolones. In the presence of Lawesson's reagent, this Pd(ii)-catalyzed annulation reaction affords another spiro-cyclopentadiene pyrazolone which displays very good fluorescence properties.
Copper-catalyzed acylation of pyrazolones with aldehydes to afford 4-acylpyrazolones
Xiao, Yan,Wu, Xiaopeng,Teng, Jiangang,Sun, Song,Yu, Jin-Tao,Cheng, Jiang
supporting information, p. 7552 - 7557 (2019/08/20)
Copper-catalyzed direct acylation of the alkenyl C-H bond in 1,2-dihydro-3H-pyrazol-3-ones has been developed, affording a series of 4-acylpyrazolones in moderate to good yields. Notably, this protocol involves readily accessible substrates and reagents, which have good functional group tolerance leading to pyrazolone derivatives under mild reaction conditions.
An easy direct arylation of 5-pyrazolones
Gong, Hao,Yang, Yiwen,Wang, Zechao,Kuang, Chunxiang
supporting information, p. 2033 - 2039 (2013/11/06)
A mild, efficient and catalytic ligand-free method for the direct arylation of 5-pyrazolones by Pd-catalyzed C-H bond activation is reported. The process smoothly proceeds and yields are moderate to excellent.
Room-temperature direct alkenylation of 5-pyrazolones
Yang, Yiwen,Gong, Hao,Kuang, Chunxiang
supporting information, p. 5276 - 5281 (2013/09/02)
A mild and efficient method for the direct alkenylation of 5-pyrazoles by Pd-catalyzed C-H bond activation is described. The reaction smoothly proceeds at room temperature to provide products in up to 92 % yield. Heterocycles containing the 5-pyrazolone moiety are synthesized by an oxidative Heck-type reaction. The direct alkenylation of 5-pyrazolones at room temperature through Pd-catalyzed C-H bond activation is described. Copyright
4-amino-2-methyl-3-phenyl-1-(2,4,6-trichlorophenyl)-3-pyrazolin-5-one
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, (2008/06/13)
Compounds are disclosed which are 4-amino-2,3-di-substituted-1-(mono- or trichlorophenyl)-3-pyrazolin-5-ones represented by the following formulae (1) to (3): STR1 and acid addition salts thereof. The compounds can be easily produced and are useful for qu
