876348-25-3

Upstream product

• 17325-85-8 (2S)-3-(benzyloxy)propane-1,2-diol 
• 111-64-8 n-octanoic acid chloride 

Downstream Products

• 876348-20-8 Octanoic acid (S)-2-(bis-benzyloxy-phosphoryloxy)-1-octanoyloxymethyl-ethyl ester 
• 113973-38-9 sn-2,3-dioctanoylglycerol 

Relevant academic research and scientific papers

Synthesis and pharmacological evaluation of second-generation phosphatidic acid derivatives as lysophosphatidic acid receptor ligands

Short-chain phosphatidic acid derivatives, dioctanoyl glycerol pyrophosphate (DGPP 8:0, 1) and phosphatidic acid 8:0 (PA 8:0, 2), were previously identified as subtype-selective LPA1 and LPA3 receptor antagonists. Recently, we report

Acetal phosphate-derived LPA mimics, PPARgamma activators, and autotaxin inhibitors

Disclosed are compositions that modulate the effects of extracellular LPA receptors, the intracellular PPARγ receptor, and autotaxin, and methods for their use.