876391-68-3

Upstream product

• 13423-48-8 triphenylheptylphosphonium bromide 
• 33797-51-2 eschenmoser's salt 
• 183129-88-6 4-(4-Octyl-phenyl)-butyraldehyde 
• 876391-67-2 ((E)-4-Oct-1-enyl)-benzaldehyde 
• 183129-84-2 4-(4'-n-octylphenyl)butan-1-ol 

Downstream Products

• 876391-73-0 phosphoric acid di-tert-butyl ester 4-[2-(4-octyl-phenyl)-ethyl]-2-trichloromethyl-4,5-dihydro-oxazol-4-ylmethyl ester 
• 876391-75-2 {(R)-4-[2-(4-Octyl-phenyl)-ethyl]-2-trichloromethyl-4,5-dihydro-oxazol-4-yl}-methanol 
• 876391-72-9 (2S)-2-(2'-(trichloromethyl)-4',5'-dihydrooxazol-5-yl)-4-(4''-octylphenyl)-butan-1-ol 
• 876391-74-1 (2R)-2-(oxiranyl)-4-(4'-octylphenyl)butan-1-ol 
• 876391-70-7 (2S)-2-(oxiranyl)-4-(4'-octylphenyl)butan-1-ol 
• 402616-26-6 (S)-fingolimod phosphate 
• 402616-23-3 FTY 520P 
• 876391-69-4 2-methylene-4-(4'-octylphenyl)butan-1-ol 

Relevant academic research and scientific papers

Chiral vinylphosphonate and phosphonate analogues of the immunosuppressive agent FTY720

The first enantioselective synthesis of chiral isosteric phosphonate analogues of FTY720 is described. One of these analogues, FTY720-(E)- vinylphosphonate (S)-5, but not its R enantiomer, elicited a potent antiapoptotic effect in intestinal epithelial ce

Enantioselective synthesis of the phosphate esters of the immunosuppressive lipid FTY720

The enantiomers of FTY720-phosphate (3) were synthesized via 2-methylene-4-(4-octylphenyl)butan-1-ol (7), 2,3-epoxy alcohol 8, and Δ2-oxazoline 10. These compounds have potential use in the treatment of autoimmune diseases and prevention of kid